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Anderson, D. J.

Publications and source records attributed to Anderson, D. J..

Chronic recording of regenerating VIIIth nerve axons with a sieve electrode

A micromachined silicon substrate sieve electrode was implanted within transected toadfish (Opsanus tau) otolith nerves. High fidelity, single unit neural activity was recorded from seven alert and unrestrained fish 30 to 60 days after implantation. Fibrous coatings of genetically engineered bioactive protein polymers and nerve guide tubes increased the number of axons regenerating through the electrode pores when compared with controls. Sieve electrodes have potential as permanent interfaces to the nervous system and to bridge missing connections between severed or damaged nerves and muscles. Recorded impulses might also be amplified and used to control prosthetic devices.

NASA Discipline Neuroscience↗

Disruption of postural readaptation by inertial stimuli following space flight

Postural instability (relative to pre-flight) has been observed in all shuttle astronauts studied upon return from orbital missions. Postural stability was more closely examined in four shuttle astronaut subjects before and after an 8 day orbital mission. Results of the pre- and post-flight postural stability studies were compared with a larger (n = 34) study of astronauts returning from shuttle missions of similar duration. Results from both studies indicated that inadequate vestibular feedback was the most significant sensory deficit contributing to the postural instability observed post flight. For two of the four IML-1 astronauts, post-flight postural instability and rate of recovery toward their earth-normal performance matched the performance of the larger sample. However, post-flight postural control in one returning astronaut was substantially below mean performance. This individual, who was within normal limits with respect to postural control before the mission, indicated that recovery to pre-flight postural stability was also interrupted by a post-flight pitch plane rotation test. A similar, though less extreme departure from the mean recovery trajectory was present in another astronaut following the same post-flight rotation test. The pitch plane rotation stimuli included otolith stimuli in the form of both transient tangential and constant centripetal linear acceleration components. We inferred from these findings that adaptation on orbit and re-adaptation on earth involved a change in sensorimotor integration of vestibular signals most likely from the otolith organs.

NASA Center JSC↗

Dynamic posture analysis of Spacelab-1 crew members

Dynamic posture testing was conducted on the science crew of the Spacelab-1 mission on a single axis linear motion platform. Tests took place in pre- and post-flight sessions lasting approximately 20 min each. The pre-flight tests were widely spaced over the several months prior to the mission while the post-flight tests were conducted over the first, second, fourth, and sixth days after landing. Two of the crew members were also tested on the day of landing. Consistent with previous postural testing conducted on flight crews, these crew members were able to complete simple postural tasks to an acceptable level even in the first few hours after landing. Our tests were designed to induce dynamic postural responses using a variety of stimuli and from these responses, evaluate subtle changes in the postural control system which had occurred over the duration of the flight. Periodic sampling post-flight allowed us to observe the time course of readaptation to terrestrial life. Our observations of hip and shoulder position, when subjected to careful analysis, indicated modification of the postural response from pre- to post-flight and that demonstrable adjustments in the dynamic control of their postural systems were taking place in the first few days after flight. For transient stimuli where the platform on which they were asked to stand quickly moved a few centimeters fore or aft then stopped, ballistic or open loop 'programs' would closely characterize the response. During these responses the desired target position was not always achieved and of equal importance not always properly corrected some 15 seconds after the platform ceased to move. The persistent observation was that the subjects had a much stronger dependence on visual stabilization post-flight than pre-flight. This was best illustrated by a slow or only partial recovery to an upward posture after a transient base-of-support movement with eyes open. Postural responses to persistent wideband pseudorandom base-of-support translation were modeled as time invarient linear systems arrived at by Kalman adaptive filter techniques. Derived model parameters such as damping factor and fundamental frequency of the closed loop system showed significant modification between pre- and post-flight. This phenomenon is best characterized by movement of the poles toward increasing stability. While pre-flight data tended to show shoulders and hips moving in phase with each other, post-flight data showed a more disjoint behavior.(ABSTRACT TRUNCATED AT 400 WORDS).

Non-NASA Center↗

Reinterpretation of otolith input as a primary factor in space motion sickness

It is hypothesized that exposure to prolonged free fall is a form of sensory/motor rearrangement rather than a direct change in otolith sensitivity or sensory compensation for a reduced otolith input. The rearrangement of stimuli will force a new interpretation by the CNS of otolith input. This reinterpretation is necessary for a structured and meaningful interaction with the new environment. Data from two flight experiments are presented which support an otolith reinterpretation hypothesis. The first experiment measured vestibulo-spinal reflex changes as a function of sustained free fall. Findings indicate that when a monosynaptic reflex (H-reflex), measured from the major postural muscles (soleus), is used adaptation to space flight includes a change in how the CNS interprets a fall. In a normal gravity environment a sudden unexpected fall will produce a potentiated H reflex. After seven days in flight an equivalent fall does not potentiate the reflex. During postflight a greatly increased reflex is observed in those crewmen most susceptible to space motion sickness. In the second experiment self motion perception and torsional eyemovements were modified as a function of exposure to sustained free fall. Preflight roll motion (about the X axis) was perceived as pure roll, and the eye movements recorded were countertorsional. Postflight, roll stimulation was perceived as linear translation (side to side movement) with a small angular motion component. Eye movement measurements confirmed significantly more horizontal motion.

Reschke, M. F.↗

The adaptation of vestibulo-spinal reflexes as a function of spaceflight and their relationship to space motion sickness

The hypothesis that exposure to prolonged free fall is a form of sensorymotor rearrangement rather than a direct change in otolith sensitivity or sensory compensation for a reduced otolith input is discussed. Data from Spacelab-1 experiment 1NS-104 are presented to support an otolith reinterpretation hypothesis. This experiment measured vestibulo-spinal reflex changes as a function of sustained free fall. Findings indicate that when a monosynaptic reflex (H-reflex), measured from the major postural muscles (soleus) is used, adaptation to space flight includes a change in how the central nervous system interprets a fall. In a normal gravity environment a sudden unexpected fall produces a potentiated H-reflex. After 7 days inflight, an equivalent fall does not potentiate the reflex. Postflight a greatly increased reflex is observed in those crewmen most susceptible to space motion sickness.

Reschke, M. F.↗

Vestibulospinal reflexes as a function of microgravity

Data from previous manned space flights suggest that an exposure to microgravity produces significant alterations in vestibular, neuromuscular, and related sensory system functions. It is possible that the observed changes are a function of adaptation induced by altered otolith input. An experiment in Spacelab 1 was conducted with the aim to study this adaptation as it occurred in flight and after flight, and to relate the observed changes to mechanisms underlying space motion sickness. The concept was explored by making use of the anatomic pathway which links the otolith organs and spinal motoneurons. The overall sensitivity of the spinal motoneurons was tested by two related methods. One method involves the electrical excitation of neural tissue and the recording of vestibulospinal reflexes in conjunction with a brief linear acceleration. The second method is concerned with measurements of dynamic postural ataxia. Results suggest that more than a single time constant may be involved in man's ability to return to baseline values.

Reschke, M. F.↗

Development and flight test of a weather radar precision approach concept

In order to make full use of the helicopter's unique capability of remote-site, off-airport landings, it would be desirable to employ a self-contained navigation system requiring minimum groundable-based equipment. For this reason, research is being conducted with the aim to develop the use of airborne weather radar as a primary navigation aid for helicopter approach and landing in instrument flight rules (IFR) conditions. Anderson et al. (1982) have reported about the first phase of this effort, taking into account the detection of passive ground-based corner reflectors with the aid of an 'echo processor'. The technology of passive-reflector detection in the overland environment provides the pilot with the range and bearing to the landing site. The present investigation is concerned with a second research phase, which was undertaken with the objective to develop and demonstrate the feasibility of a weather radar-based precision approach concept. Preliminary flight test results are considered.

Clary, G. R.↗

Design considerations for a real-time ocular counterroll instrument

A real-time algorithm for measuring three-dimensional movement of the human eye, especially torsional movement, is presented. As its input, the system uses images of the eyeball taken at video rate. The amount of horizontal and vertical movement is extracted using a pupil tracking technique. The torsional movement is then measured by computing the discrete cross-correlation function between the circular samples of successive images of the iris patterns and searching for the position of the peak of the function. A local least square interpolation around the peak of the cross-correlation function is used to produce nearly unbiased estimates of torsion angle with accuracy of about 3-4 arcmin. Accuracies of better than 0.03 deg are achievable in torsional measurement with SNR higher than 36 dB. Horizontal and vertical rotations of up to + or - 13 deg can occur simultaneously with torsion without introducing any appreciable error in the counterrolling measurement process.

Hatamian, M.↗

Demonstration of radar reflector detection and ground clutter suppression using airborne weather and mapping radar

A navigation system which utilizes minimum ground-based equipment is especially advantageous to helicopters, which can make off-airport landings. Research has been conducted in the use of weather and mapping radar to detect large radar reflectors overland for navigation purposes. As initial studies have not been successful, investigations were conducted regarding a new concept for the detection of ground-based radar reflectors and eliminating ground clutter, using a device called an echo processor (EP). A description is presented of the problems associated with detecting radar reflectors overland, taking into account the EP concept and the results of ground- and flight-test investigations. The echo processor concept was successfully demonstrated in detecting radar reflectors overland in a high-clutter environment. A radar reflector target size of 55 dBsm was found to be adequate for detection in an urban environment.

Anderson, D. J.↗

Flight tests of IFR landing approach systems for helicopters

Joint NASA/FAA helicopter flight tests were conducted to investigate airborne radar approaches (ARA) and microwave landing system (MLS) approaches. Flight-test results were utilized to prove NASA with a data base to be used as a performance measure for advanced guidance and navigation concepts, and to provide FAA with data for establishment of TERPS criteria. The first flight-test investigation consisted of helicopter IFR approaches to offshore oil rigs in the Gulf of Mexico, using weather/mapping radar, operational pilots, and a Bell 212 helicopter. The second flight-test investigation consisted of IFR MLS approaches at Crows Landing (near Ames Research Center), with a Bell UH-1H helicopter, using NASA, FAA, and operational industry pilots. Tests are described and results discussed.

Bull, J. S.↗

NASA/FAA flight-test investigation of helicopter microwave landing system approaches

The helicopter Microwave Landing System flight-test investigations, conducted by a joint NASA/FAA effort in order to gather statistical data for establishing terminal instrument procedures criteria, and to provide a performance data base for developing advanced MLS guidance concepts, are presented. The specific flight-test objectives were to: (1) develop acceptable angle-only MLS approach profiles; (2) determine tracking errors; (3) determine altitude loss during missed approach; (4) evaluate guidance display sensitivities; and (5) evaluate pilot acceptability. Fourteen pilots flew 140 manual (without stability augmentation) dual-pilot simulated instrument approaches in a UH-1H helicopter. The flight profiles flown included 3-, 6-, and 9-degree glideslope, centerline approaches to decision heights of 50, 100, and 150 ft, respectively. The angular guidance display sensitivities and the data acquisition system are also described. Eight major conclusions are made, and include the following: (1) the use of pitch attitude to control airspeed and collective to control glideslope was the preferred pilot technique for the steep glideslope approaches, and (2) angular guidance deviation indicator sensitivity requirements for helicopter MLS approaches to STOLports and heliports have been found to be significantly different from standard ILS sensitivities.

Peach, I. L., Jr.↗

Evaluation of postural mechanisms under dynamic conditions

A stimulus delivery and data acquisition system for assessment of human posture was developed based on a digital computer and a translating platform. The movement of the platform acts to displace the subject's base of support while the computer tracks the corrections which are made by the subject to maintain balance. Various stimuli are used ranging from fast transients to sine waves.

Anderson, D. J.↗

The detection and analysis of point processes in biological signals

A pragmatic approach to the detection and analysis of discrete events in biomedical signals is taken. Examples from both clinical and basic research are provided. Introductory sections discuss not only discrete events which are easily extracted from recordings by conventional threshold detectors but also events embedded in other information carrying signals. The primary considerations are factors governing event-time resolution and the effects limits to this resolution have on the subsequent analysis of the underlying process. The analysis portion describes tests for qualifying the records as stationary point processes and procedures for providing meaningful information about the biological signals under investigation. All of these procedures are designed to be implemented on laboratory computers of modest computational capacity.

Anderson, D. J.↗