Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
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99 GENERAL AND MISCELLANEOUS↗
Engineering topics
Christianson, D.
Publications and source records attributed to Christianson, D..
Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase
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99 GENERAL AND MISCELLANEOUS↗
An Aromatic Cluster in the Active Site of epi-Isozizaene Synthase Is an Electrostatic Toggle for Divergent Terpene Cyclization Pathways
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99 GENERAL AND MISCELLANEOUS↗
Structure and Function of the Acetylpolyamine Amidohydrolase from the Deep Earth Halophile Marinobacter subterrani
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99 GENERAL AND MISCELLANEOUS↗
Unique Molecular Interaction with the Histone Deacetylase 6 Catalytic Tunnel: Crystallographic and Biological Characterization of a Model Chemotype
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99 GENERAL AND MISCELLANEOUS↗
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors
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99 GENERAL AND MISCELLANEOUS↗
Structural Basis for the Selective Inhibition of HDAC10, the Cytosolic Polyamine Deacetylase
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99 GENERAL AND MISCELLANEOUS↗
Binding of inhibitors to active-site mutants of CD1, the enigmatic catalytic domain of histone deacetylase 6
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99 GENERAL AND MISCELLANEOUS↗
Higher-order oligomerization of a chimeric αβγ bifunctional diterpene synthase with prenyltransferase and class II cyclase activities is concentration-dependent
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99 GENERAL AND MISCELLANEOUS↗
Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of the Phosphomimetic S39E Mutant
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99 GENERAL AND MISCELLANEOUS↗
Binding of N-8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation
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99 GENERAL AND MISCELLANEOUS↗
Crystal Structure of Cucumene Synthase, a Terpenoid Cyclase That Generates a Linear Triquinane Sesquiterpene
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99 GENERAL AND MISCELLANEOUS↗
Structural Basis of Tryptophan Reverse N-Prenylation Catalyzed by CymD
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99 GENERAL AND MISCELLANEOUS↗
Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor
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99 GENERAL AND MISCELLANEOUS↗
Improved method of signature extraction
System promises capability of rapidly processing large amounts of data generated by currently available and planned multispectral sensors, such as those utilized on aircraft and spacecraft. Techniques developed for system, greatly decrease operator time required for signature extraction from multispectral data base.
Christianson, D.↗