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Cohen, Jonathan

Publications and source records attributed to Cohen, Jonathan.

7 records
All sourcesNASA NTRSDOE OSTI
DOE OSTI2016

Home Rx: The Health Benefits of Home Performance

Evidence in a new, groundbreaking U.S. Department of Energy report, Home Rx: The Health Benefits of Home Performance, shows that home performance upgrades can improve the quality of a home’s indoor environment by reducing the prevalence of harmful indoor air pollutants and contaminants. Until recently, no systematic review of this evidence had been conducted, limiting full understanding of the link between home performance and health. This new report summarizes current knowledge and identifies research gaps. The design characteristics and results of each of the 40 studies considered in the report are summarized in a searchable matrix.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗
DOE OSTI2016

Stereotactic Radiosurgery for Brainstem Metastases: An International Cooperative Study to Define Response and Toxicity

Purpose: To pool data across multiple institutions internationally and report on the cumulative experience of brainstem stereotactic radiosurgery (SRS). Methods and Materials: Data on patients with brainstem metastases treated with SRS were collected through the International Gamma Knife Research Foundation. Clinical, radiographic, and dosimetric characteristics were compared for factors prognostic for local control (LC) and overall survival (OS) using univariate and multivariate analyses. Results: Of 547 patients with 596 brainstem metastases treated with SRS, treatment of 7.4% of tumors resulted in severe SRS-induced toxicity (grade ≥3, increased odds with increasing tumor volume, margin dose, and whole-brain irradiation). Local control at 12 months after SRS was 81.8% and was improved with increasing margin dose and maximum dose. Overall survival at 12 months after SRS was 32.7% and impacted by age, gender, number of metastases, tumor histology, and performance score. Conclusions: Our study provides additional evidence that SRS has become an option for patients with brainstem metastases, with an excellent benefit-to-risk ratio in the hands of experienced clinicians. Prior whole-brain irradiation increases the risk of severe toxicity in brainstem metastasis patients undergoing SRS.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2012

LULESH Programming Model and Performance Ports Overview

This document gives a description of various versions of the LULESH proxy application described in [1]. All the the codes described in this document are available at https://codesign.llnl. gov/lulesh.php. This report describes versions that fall into three categories: performance tuning exploration, programming model exploration and other versions. In this document we focus on giving a brief overview of what makes each version different from the others. The purpose is to allow others to reuse our work as a starting point for their exploration. Therefore, references to publications and presentations are provided to allow those who want more detailed information to be able to find it.

97 MATHEMATICS AND COMPUTING↗