Engineering topics
Publications and source records attributed to Davis, Jeffery T..
Compositions, local structures and interactions of medicinally relevant small molecules added to G-quartet hydrogels are characterized using gel-state NMR spectroscopy.
A disulfide made by oxidation of 8-thioguanosine is a supergelator. The hydrogels are redox-responsive, as they disassemble upon either reduction or oxidation of the S–S bond. We also identified this disulfide, and 2 other compounds, as intermediates in oxidative desulfurization of 8-thioG to guanosine.
This report describes the history and accomplishments of DE-FG02-98ER14888. The project focuses on synthesis and characterization of self-assembled ionophores for remediation and separation of various cations and anions.