Biodetection-DHSS&T visit [Slides]
Presentation slides that discuss the biodetection capabilities present at Los Alamos National Laboratory (LANL).
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
Engineering topics
Deshpande, Alina
Publications and source records attributed to Deshpande, Alina.
Warning Signs of Potential Black Swan Outbreaks in Infectious Disease
Black swan events in infectious disease describe rare but devastatingly large outbreaks. While experts are skeptical that such events are predictable, it might be possible to identify the warning signs of a black swan event. Specifically, following the initiation of an outbreak, key differentiating features could serve as alerts. Such features could be derived from meta-analyses of large outbreaks for multiple infectious diseases. We hypothesized there may be common features among the pathogen, environment, and host epidemiological triad that characterize an infectious disease black swan event. Using Los Alamos National Laboratory’s tool, Analytics for Investigation of Disease Outbreaks, we investigated historical disease outbreak information and anomalous events for several infectious diseases. By studying 32 different infectious diseases and global outbreaks, we observed that in the past 20–30 years, there have been potential black swan events in the majority of infectious diseases analyzed. Importantly, these potential black swan events cannot be attributed to the first introduction of the disease to a susceptible host population. This paper describes our observations and perspectives and illustrates the value of broad analysis of data across the infectious disease realm, providing insights that may not be possible when we focus on singular infectious agents or diseases. Data analytics could be developed to warn health authorities at the beginning of an outbreak of an impending black swan event. Such tools could complement traditional epidemiological modeling to help forecast future large outbreaks and facilitate timely warning and effective, targeted resource allocation for mitigation efforts.
60 APPLIED LIFE SCIENCES↗
Key Pandemic Response R&D Contributions by Los Alamos National Laboratory
New research goals, mitigation successes, and beneficial collaborations burgeoned from the early critical days of 2020 when LANL (Los Alamos National Laboratory) pivoted to help respond to the pandemic. By applying its considerable capabilities in the fields of science, technology, and engineering (STE), LANL responded to the coronavirus infectious disease (COVID-19) pandemic. This report documents representative examples of that response. Through significant investments in COVID-19 mitigations and ongoing research and development (R&D), important advancements were made to address the pandemic that not only benefited the global population affected by the pandemic, but also protected our staff and collaborators as we executed our Lab’s mission.
59 BASIC BIOLOGICAL SCIENCES↗