FDX5 deletion affects metabolism of algae during the different phases of S-deprivation
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Engineering topics
Publications and source records attributed to Dubini, Alexandra.
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Ferredoxins are proteins that mediate electron transfer in a number of biological reactions, providing reductant (or oxidant) to a variety of metabolic pathways. In Chlamydomonas, 13 ferredoxin gene homologs have been identified, and their role in algal metabolism is being investigated. We describe the current state of the research related to Chlamydomonas ferredoxins FDX1, FDX2, and FDX5, particularly with respect to pathways involved in H2 production. Furthermore, we provide a global understanding of the possible role(s) of all Chlamydomonas ferredoxins, based on comparison with ferredoxins from other organisms. The information presented in this review is expected to provide new directions specifically towards H2-related ferredoxin research in photosynthetic organisms in general.
This chapter provides an overview of the current state of knowledge of the mechanisms involved in biohydrogen production from microalgae. The known limitations linked to photohydrogen productivity are addressed. Particular attention is given to physiological and molecular strategies to sustain and improve hydrogen production. The impact of different nutrient stresses and the effect of carbon supply on hydrogen production are discussed. The genetic and metabolic engineering approaches for increasing hydrogen production are outlined.