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Fortman, Jeffrey L

Publications and source records attributed to Fortman, Jeffrey L.

Producing a trimethylpentanoic acid using hybrid polyketide synthases

The present invention provides for a polyketide synthase (PKS) capable of synthesizing trimethylpentanoic acid. The present invention also provides for a host cell comprising the PKS and when cultured produces the trimethylpentanoic acid. The present invention also provides for a method of producing the trimethylpentanoic acid, comprising: providing a host cell of the present invention, and culturing said host cell in a suitable culture medium such that the trimethylpentanoic acid is produced, optionally isolating the trimethylpentanoic acid, and optionally, reducing the isolated trimethylpentanoic acid into a trimethylpentanol or an iso-octane.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Producing dicarboxylic acids using polyketide synthases

The present invention provides for a polyketide synthase (PKS) capable of synthesizing a dicarboxylic acid (diacid). Such diacids include diketide-diacids and triketide-diacids. The invention includes recombinant nucleic acid encoding the PKS, and host cells comprising the PKS. The invention also includes methods for producing the diacids.

60 APPLIED LIFE SCIENCES↗