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Hashimoto, M

Publications and source records attributed to Hashimoto, M.

12 records
All sourcesNASA NTRSDOE OSTI
DOE OSTI2015

SU-E-T-437: Four-Dimensional Treatment Planning for Lung VMAT-SBRT

Purpose: To assess optimal treatment planning approach of Volumetric Modulated Arc Therapy for lung Stereotactic Body Radiation Therapy (VMAT-SBRT). Methods: Subjects were 10 patients with lung cancer who had undergone 4DCT. The internal target volume (ITV) volume ranged from 2.6 to 16.5cm{sup 3} and the tumor motion ranged from 0 to 2cm. From 4DCT, which was binned into 10 respiratory phases, 4 image data sets were created; maximum intensity projection (MIP), average intensity projection (AIP), AIP with the ITV replaced by 0HU (RITV-AIP) and RITV-AIP with the planning target volume (PTV) minus the internal target volume was set to −200 HU (HR-AIP). VMAT-SBRT plans were generated on each image set for a patient. 48Gy was prescribed to 95% of PTV. The plans were recalculated on all phase images of 4DCT and the dose distributions were accumulated using a deformable image registration software MIM Maestro™ as the 4D calculated dose to the gross tumor volume (GTV). The planned dose to the ITV and 4D calculated dose to the GTV were compared. Results: In AIP plan, 10 patients average of all dose parameters (D1%, D-mean, and D99%) discrepancy were 1Gy or smaller. MIP and RITV-AIP plans resulted in having common tendency and larger discrepancy than AIP plan. The 4D dose was lower than the planned dose, and 10 patients average of all dose parameters discrepancy were in range 1.3 to 2.6Gy. HR-AIP plan had the largest discrepancy in our trials. 4D calculated D1%, D-mean, and D99% were resulted in 3.0, 4.1, and 6.1Gy lower than the expected in plan, respectively. Conclusion: For all patients, the dose parameters expected in AIP plan approximated to 4D calculated. Using AIP image set seems optimal treatment planning approach of VMAT-SBRT for a mobile tumor. Funding Support: This work was supported by the Japan Society for the Promotion of Science Core-to-Core program (No. 23003)

60 APPLIED LIFE SCIENCES↗
DOE OSTI2014

SU-E-CAMPUS-T-03: Four-Dimensional Dose Distribution Measurement Using Plastic Scintillator

Purpose: To develop the detector for the four-dimensional dose distribution measurement. Methods: We made the prototype detector for four-dimensional dose distribution measurement using a cylindrical plastic scintillator (5 cm diameter) and a conical reflection grass. The plastic scintillator is used as a phantom. When the plastic scintillator is irradiated, the scintillation light was emitted according to absorbed dose distribution. The conical reflection grass was arranged to surround the plastic scintillator, which project to downstream the projection images of the scintillation light. Then, the projection image was reflected to 45 degree direction by flat reflection grass, and was recorded by camcorder. By reconstructing the three-dimensional dose distribution from the projection image recorded in each frame, we could obtain the four-dimensional dose distribution. First, we tested the characteristic according to the amount of emitted light. Then we compared of the light profile and the dose profile calculated with the radiotherapy treatment planning system. Results: The dose dependency of the amount of light showed linearity. The pixel detecting smaller amount of light had high sensitivity than the pixel detecting larger amount of light. However the difference of the sensitivity could be corrected from the amount of light detected in each pixel. Both of the depth light profile through the conical reflection grass and the depth dose profile showed the same attenuation in the region deeper than peak depth. In lateral direction, the difference of the both profiles was shown at outside field and penumbra region. We consider that the difference is occurred due to the scatter of the scintillation light in the plastic scintillator block. Conclusion: It was possible to obtain the amount of light corresponding to the absorbed dose distribution from the prototype detector. Four-dimensional dose distributions can be reconstructed with high accuracy by the correction of the scattered light.

07 ISOTOPE AND RADIATION SOURCES↗
DOE OSTI2012

Nucleosynthesis in a massive star associated with magnetohydrodynamical jets from collapsars

We investigate the nucleosynthesis during the stellar evolution and the jet-like supernova explosion of a massive star of 70 M{sub Circled-Dot-Operator} having the solar metallicity in the main sequence stage. The nucleosynthesis calculations have been performed with large nuclear reaction networks, where the weak s-, p-, and r-processes are taken into account. As a result s-elements of 60 > A > 90 and r-elements of 90 > A > 160 are highly overproduced relative to the solar system abundances. We find that the Sr-Y-Zr isotopes are primarily synthesized in the explosive nucleosynthesis which could be one of the sites of the lighter element primary process (LEPP).

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗
DOE OSTI2011

Nucleosynthesis in neutrino-driven, aspherical supernova explosion of a massive star

We examine explosive nucleosynthesis of p-nuclei during a delayed neutrino-driven, aspherical supernova explosion aided by standing accretion shock instability, based on two-dimensional hydrodynamic simulations of the explosion of a 15M{sub {center_dot}} star. We find that p-nuclei are mainly produced through {gamma}-processes, and that the nuclei lighter than {sup 92}Mo are abundantly synthesized in slightly neutron-rich bubbles with electron fractions of Y{sub e}{<=}0.48. {sup 94}Mo, {sup 96}Ru, and {sup 98}Ru, are underproduced compared with the solar system, as in the spherical model.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗
DOE OSTI2011

Nucleosynthesis in Magnetohydrodynamical Jets from Collapsars

We investigate the heavy-element nucleosynthesis of a massive star whose mass in the main sequence stage is M{sub ms} = 70 M{sub {center_dot}}. Detailed calculations of the nucleosynthesis are performed during the hydrostatic stellar evolution until the core composed of iron-group nuclei begins to collapse. As a supernova explosion model, a collapsar model is constructed whose jets are driven by magnetohydrodynamical effects of a differentially rotating core. The heavy-element nucleosynthesis inside the jet of a collapsar model is followed along the trajectories of stream lines of the jet. We combine the results of both hydrostatic and heavy-element nucleosyntheses to compare with the solar abundances. We find that neutron-rich elements of 70<A<140 are highly overproduced relative to the solar abundances. Therefore, we conclude that this scenario should be rare and elements of A < or approx. 70 are compensated for other supernova explosion models. We find also that different mass formula changes significantly the production of elements of A>140.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗
DOE OSTI2011

R-process Nucleosynthesis in Supernova Explosion

We investigate the possibility of the r-process during the magnetohydrodynamical (MHD) explosion of supernova in a massive star of 13 M{sub {center_dot}} with the effects of neutrinos included. Contrary to the case of the spherical explosion, jet-like explosion due to the combined effects of rotation and magnetic field lowers the electron fraction significantly inside the layers. We find that the ejected material of low electron fraction responsible for the r-process comes out from the inner deep region of the core that is made up of iron-group nuclei. This leads to the production of the second to third peak in the solar r-process elements. We suggest that there are some variations in the r-process nucleosynthesis according to the initial conditions of rotational and magnetic fields.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗