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Hecht, J.

Publications and source records attributed to Hecht, J..

Human Bone-Forming Chondrocytes Cultured in the Hydrodynamic Focusing Bioreactor Retain Matrix Proteins: Similarities to Spaceflight Results

Fracture healing, crucial to a successful Mars mission, involves formation of a cartilaginous fracture callus which differentiates, mineralizes, ossifies and remodels via the endochondral process. Studies of spaceflown and tailsuspended rats found that, without loading, fracture callus formation and cartilage differentiation within the callus were minimal. We found delayed differentiation of chondrocytes within the rat growth plate on Cosmos 1887, 2044, and Spacelab 3. In the current study, differentiation of human bone-forming chondrocytes cultured in the hydrodynamic focusing bioreactor (HFB) was assessed. Human costochondral chondrocytes in suspension were aggregated overnight, then cultured in the HFB for 25 days. Collagen Type II, aggrecan and unsulfated chondroitin were found extracellularly and chondroitin sulfates 4 and 6 within the cell. Lack of secretion was also found in pancreatic cells of spaceflown rats, and in our SL3 studies. The HFB can be used to study cartilage differentiation in simulated microgravity.

Duke, P. J.↗

Atmospheric response in aurora experiment: Observations of E and F region neutral winds in a region of postmidnight diffuse aurora

The goal of the Atmospheric Response in Aurora (ARIA) experiment carried out at Poker Flat, Alaska, on March 3, 1992, was to determine the response of the neutral atmosphere to the long-lived, large-scale forcing that is characteristic of the diffuse aurora in the post midnight sector. A combination of chemical release rocket wind measurements, instrumented rocket composition measurements, and ground-based optical measurements were used to characterize the response of the neutral atmosphere. The rocket measurements were made at the end of a 90-min period of strong Joule heating. We focus on the neutral wind measurements made with the rocket. The forcing was determined by running the assimilated mapping of ionospheric electrodynamics (AMIE) analysis procedure developed at the National Center for Atmospheric Research. The winds expected at the latitude and longitude of the experiment were calculated using the spectral thermospheric general circulation model developed at the Danish Meteorological Institute. Comparisons of the observations and the model suggest that the neutral winds responded strongly in two height ranges. An eastward wind perturbation of approximately 100 m/s developed between 140 and 200 km altitude with a peak near 160 km. A southwestward wind with peak magnitude of approximately 150 m/s developed near 115 km altitude. The large amplitude winds at the lower altitude are particularly surprising. They appear to be associated with the upward propagating semidiurnal tide. However, the amplitude is much larger than predicted by any of the tidal models, and the shear found just below the peak in the winds was nominally unstable with a Richardson number of approximately 0.08.

Larsen, M. F.↗

The fading of R Coronae Borealis

Using the International Ultraviolet Explorer (IUE) low-resolution spectra were obtained of R CrB, the prototype of its class of variable stars, shortly after the beginning of its 1983-84 minimum and during its rise to maximum again. The behavior of the spectra during the rise to maximum is similar to the behavior of the spectra of RY Sgr during a similar phase in 1979-80. The extinction data have been analyzed using Mie theory and are consistent with the stellar photosphere being obscured by 20-nm glassy carbon particles. The observations during the decline to minimum show substantial spectral variations which cannot be explained in terms of simple continuum absorption. An interpretation of the observed behavior in terms of a model incorporating an occulting cloud and circumstellar emission is offered.

Holm, A. V.↗

The peculiar extinction of Herschel 36

The extinction of Herschel 36 has been measured and been found to be peculiar in the same sense as that observed in Orion. Following the treatment of Mathis and Wallenhorst (1981), this can be explained by the presence of silicate and graphite grains that are larger than those normally found in the interstellar medium. Correcting the stellar flux for foreground extinction results in a residual extinction curve for the associated dust cloud with an unusually small normalized extinction (less than 1.0) at 1500 A. This low UV extinction may be due to the effects of scattering by the dust cloud material.

Hecht, J.↗

Experiments and calculations on the extinction of starlight by iron or magnetite grains

Both iron and magnetite have previously been proposed as constituents of interstellar grains. If either type of magnetic grain exists, it would help to explain the polarization of starlight which is thought to be caused by grains aligned by the interstellar magnetic field. A description is presented of laboratory measurements and computer calculations of the optical properties of small (approximately 25 nm radius) Fe and Fe304 grains. These results are discussed in terms of the effect of such particles on the extinction observed in the interstellar medium or in circumstellar shells. It is found that Fe is probably not responsible for the 220 nm feature in the interstellar extinction curve. Calculations show that if Fe304 is responsible for the very broad structure (VBS) in the interstellar extinction curve, then it would also be a significant contributor to the extinction in the near-UV.

Hecht, J.↗

The peculiar UV extinction of Herschel 36

The differential extinction curve of Herschel 36 was determined from International Ultraviolet Explorer data. It is quite unusual, characterized by a distinct 2200 A peak with a very low far blue end at 5 to 7 mu to the -1 power. The star appears to be an extreme member of the group Savage drew attention to, previously consisting only of theta Ori, NU Ori, sigma Sco, and rho Oph. It appears that multiple scattering effects are needed to explain the observations.

Hecht, J.↗

Interstellar extinction by small-coated or uncoated graphite grains

Calculations have been made on the theoretical extinction of spherical graphite particles from 130 to 3500 nm. It is found that graphite particles of radius near 20 nm can have small (0.5 nm) coatings and still be responsible for the 220 nm peak in the interstellar extinction curve. New calculations also show that the effect of finite particle size is relatively unimportant in determining the extinction of graphite spheres at 220 nm.

Hecht, J.↗