A conserved epitope III on hepatitis C virus E2 protein has alternate conformations facilitating cell binding or virus neutralization
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Engineering topics
Publications and source records attributed to Holcomb, D..
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Molten Salt Reactors (MSRs) have seen a resurgence of interest in the past decade around the world. Support for these activities is provided from both national and private sources. The largest difference from the 2011 GIF MSR PR&PP evaluation consequently is the transition from evaluating academic systems focused on exploring the technical potential of MSRs to those of companies and countries focusing on near-term deployment. A wide variety of designs currently exist ranging from solid to liquid-fueled designs, with salt processing on-site or off-site, and a variety of fuel choices. As such, the proliferation resistance and physical protection aspects will have significantly more variation depending on reactor design than the other advanced reactors. The rapid introduction and evolution of innovative MSR designs inevitably means that technology specific details of overview reports, such as this one, become rapidly outdated. Consequently, this report focuses on essential features required for any MSR rather than specific design aspects.
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Holographic interferometry and finite element analysis have been applied to determine the strain in a large optical window installed in a high-pressure chamber. Two different shapes of windows were chosen, and the outside and inside surface strains of the windows were followed as a function of internal pressure by taking double exposed holograms at 69-bar intervals up to 483 bars. The results were compared with the values calculated by a standard finite element code with an assumption of no displacement at the load-bearing edge. The agreement between two results was found to be good for both cases.