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Holmes, A.

Publications and source records attributed to Holmes, A..

X-ray Microscopic Characterization of Protein Crystals

The microscopic mapping of the variation in degree of perfection and in type of defects in entire protein crystals by x-rays may well be a prerequisite for better understanding causes of lattice imperfections, the growth history, and properties of protein crystals. However, x-ray microscopic characterization of bulk protein crystals, in the as-grown state, is frequently more challenging than that of small molecular crystals due to the experimental difficulties arising largely from the unique features possessed by protein crystals. In this presentation, we will illustrate ssme recent activities in employing coherence-based phase contrast x-ray imaging and high-angular-resolution diffraction techniques for mapping microdefects and the degree of perfection of protein crystals, and demonstrate a correlation between crystal perfection, diffraction phenomena., and crystallization conditions. The observed features and phenomena will be discussed in context to gain insight into the nature of defects, nucleation and growth, and the properties of protein crystals.

Hu, Z. W.↗

Pioneer Venus Sounder Probe Solar Flux Radiometer

The Solar Flux Radiometer aboard the Pioneer Venus Sounder Probe operated successfully during its descent through the atmosphere of Venus. The instrument measured atmospheric radiance over the spectral range from 400 to 1800 nm as a function of altitude. Elevation and azimuthal measurements on the radiation field were made with five optical channels. Twelve filtered Si and Ge photovoltaic detectors were maintained near 30 C with a phase-change material. The detector output currents were processed with logarithmic transimpedance converters and digitized with an 11-bit A/D converter. Atmospheric sampling in both elevation and azimuth was done according to a Gaussian integration scheme. The serial output data averaged 20 bits/sec, including housekeeping (sync, spin period, sample timing and mode). The data were used to determine the deposition of solar energy in the atmosphere of Venus between 67 km and the surface along with upward and downward fluxes and radiances with an altitude resolution of several hundred meters. The results allow for more accurate modeling of the radiation balance of the atmosphere than previously possible.

Tomasko, M. G.↗

Narrow-field radiometry in a quasi-isotropic atmosphere

If a radiometer having a narrow field of view is used to measure the radiance of a source such as a quasi-isotropic atmosphere, a knowledge of the out-of-field responsivity is critical. For example, if a radiometer with a field of view of 5 deg (full-angle) has a relative responsivity of 0.0001 for the out-of-field radiation, the contribution of the out-of-field radiation (assuming an isotropic source subtending 2 steradians) is 10.5% of the total signal. Either the stray light suppression of the radiometer must be extremely high or methods of determining the out-of-field response must be developed. A description of one method of determining the effect of out-of-field response and its application to a planetary atmospheric radiometer is presented.

Holmes, A.↗