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Li, Rachel

Publications and source records attributed to Li, Rachel.

Deficiency in transmitter release triggers homeostatic transcriptional changes that increase presynaptic excitability

Weakening of synaptic transmission at theDrosophilalarval neuromuscular junction triggers two forms of homeostatic compensation, one that increases the probability of glutamate release per action potential (P r ) and another that increases motoneuron (MN) activity. We investigated the molecular changes in MNs that underlie the increase in MN activity. RNA sequencing (RNA-seq) analysis on MNs whose glutamate release is weakened by knockdown of components of the MN transmitter release machinery reveals a reduction in expression of a group of genes that encode potassium channels and their positive modulators. These results identify a mechanism of compensation for weakened synaptic transmission by MNs, which engages a transcriptional program in those cells to increase firing and, thereby, ensure sufficient locomotory drive.

Science & Technology - Other Topics

Citizen Science Twitter Data Management for Earth Science Applications

Social media data can provide useful real-time and historical information relating to the natural world, but managing this data poses challenges. Scientists at GES DISC are exploring the potential of Twitter data to augment precipitation data from the Global Precipitation Measurement (GPM) mission. However, the format of Twitter data is unconventional in the context of NASA data centers, resulting in frustration for scientists who need to work with the data. This study investigated procedures and standards needed to properly manage Twitter data to make them compatible with these data centers. After comparing databases, the study found that the MongoDB database was best suited for the storage of raw Twitter data due to its flexibility, ability to be accessed by multiple users, and querying functionality. The study used the Python package Zarr to transform processed Twitter data into a gridded format similar to that of satellite data. Each Tweet was mapped onto a time-space grid; each grid location contained information about Tweet attributes and precipitation. The study developed a pipeline for downloading, storing, and gridding Twitter data and transformed Twitter data into an understandable format for users of NASA satellite data.

Li, Rachel

Developing a Machine-Learning-Based Processing Framework for Twitter and Other Crowdsourced Data

Crowdsourced data streams such as Twitter and other social media are important sources of real-time and historical global information for Earth science applications. At the NASA Goddard Earth Sciences Data and Information Services Center (GES DISC), we have been exploring the Twitter data stream for its potential in augmenting the validation program of NASA's Global Precipitation Measurement (GPM) mission. To realize this potential, we need to increase the information density and enhance the quality of filtered precipitation tweets. We have implemented various components of a machine learning (ML)-based processing infrastructure for crowdsourced data that outputs, in this instance, useful and usable information derived from precipitation tweets. We have test enriched the Twitter stream with higher quality active tweets from those knowingly contributing to our effort and from existing crowdsourced programs (e.g., mPING, CoCoRaHS). We have experimented with various algorithms for processing tweets, including Naà ve Bayes, Convolutional Neural Network (CNN), Hierarchical Attention Network (HAN), and semi-supervised learning (with tri-training). Our current work focuses on (1) automated review of Earth science-related publications to determine relationships between discipline research needs and ML algorithms; (2) investigating Sequential Generative Adversarial Network (SeqGAN) for processing precipitation tweets for anomaly detection; and (3) managing crowdsourced data in a way that is compatible with existing NASA satellite data archives and using the data for ML applications. Key results include (1) network visualization of NLP-processed publications in various Earth science disciplines; (2) difference between GPM-linked, generated tweets and collected actual tweets that is small for GPM-determined light to moderate rain cases and high for GPM-determined heavy rain cases; and (3) identification of MongoDB for storing raw tweets and Zarr format for gridded tweets (compatible with GPM data). Our results have taken us a step closer to an operational ML-based tweet processing infrastructure and have already demonstrated that tweet-derived precipitation information is potentially useful for validation of Earth science satellite data.

Teng, William