Engineering topics
Publications and source records attributed to Lindberg, R. G..
Studies carried out on the pocket mouse colony on Apollo XVII are reported. They revealed no serological evidence of viral disease, no pathogenic enterobacteria or respiratory Mycoplasma on culture, a 25% incidence of sarcosporidiosis, and a 2% incidence of chronic meningitis or meningoencephalitis. It is concluded that the pocket mouse is a highly adaptive animal and very well-suited to space flight.
A closed passive system independent of support from the spacecraft or its crew was developed to house five pocket mice for their flight on Apollo XVII. The reaction of potassium superoxide with carbon dioxide and water vapor to produce oxygen provided a habitable atmosphere within the experiment package. The performance of the system and the ability of the mice to survive the key preflight tests gave reasonable assurance that the mice would also withstand the Apollo flight.-
Three areas of inquiry are reported for the Skylab Experiment S-071 whose objective was to study the circadian system of a mammal during space flight. The thermoregulatory behavior of the Perognathus longimembris, or little pocket mouse, was studied under conditions of constant dark and constant temperature in the prolonged weightless environment of Skylab. The following specific questions were studied: (1) the effects of weightlessness on circadian periodicity in the little pocket mouse; (2) stability of the free-running circadian period of body temperature of the little pocket mouse exposed to simulated launch stress; and (3) characteristics of the circadian rhythm of body temperature in the little pocket mouse. Diagrams of the electronic circuitry and hardware used in the experiment are shown and results are given in both graphical and tabular form. The methods used in the experiment are fully documented, along with conclusions and recommendations for future research.
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Investigation of the response of pocket mice to Co 60 irradiation delivered at two times of day - namely, the predicted high and low points of the metabolic rate. The validity of torpor as an assay of the circadian period of body temperature in pocket mice and as a basis for selecting irradiation times is examined. A study is made of the mitotic activity in the pocket mouse intestinal epithelium as an example of a physiological rhythm which might influence radiation sensitivity. The results of tests in which pocket mice were exposed to ionizing radiation at two different times of day are cited. It is found that under the investigated conditions pocket mice irradiated during their metabolically active period (2330 hr) live significantly longer than those irradiated while their metabolic rate is low (0900 hr).
Diurnal pressure cycles found as zeitgeber to entrain body temperature endogenous circadian rhythm in pocket mice under constant environmental temperature and light
Physiology of pocket mice and suitability for exobiology research in biosatellites
Engineering feasibility of biological experiments aboard Pioneer space probes
Hypoxia induced hypothermia and hemoglobin oxygen affinity in Perognatus
Temperature regulation and acclimatization in pocket mouse, perognathus longimembris
Temperature regulation in pocket mouse for space biology research
Body temperature regulatory mechanism and extreme environment response of pocket mouse
Hibernation characteristics of pocket mice and temperature effect on torpidity
Anatomical brain structure of Perognathus longimembris
Animal temperature sensing for studying effect of prolonged orbital flight on circadian rhythms of pocket mice
Investigation of Perognathus as experimental organism for research in space biology - reproductive cycles, breeding and rearing in captivity
Reproduction of mice in confinement
Histopathology of pocket mouse intestine mucous after irradiation - growth and development data on laboratory pocket mouse