Development of BET inhibitors as potential treatments for cancer: A search for structural diversity
Explore the source record for details and available documents.
Hill, Matthew D.↗
Engineering topics
Morrison, John
Publications and source records attributed to Morrison, John.
Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor K
Explore the source record for details and available documents.
Degnan, Andrew P.↗
Trinity to Trinity 1945-2015
The Trinity Test of July 16, 1945 was the first full-scale, real-world test of a nuclear weapon; with the new Trinity supercomputer Los Alamos National Laboratory's goal is to do this virtually, in 3D. Trinity was the culmination of a fantastic effort of groundbreaking science and engineering by hundreds of men and women at Los Alamos and other Manhattan Project sites. It took them less than two years to change the world. The Laboratory is marking the 70th anniversary of the Trinity Test because it not only ushered in the Nuclear Age, but with it the origin of today’s advanced supercomputing. We live in the Age of Supercomputers due in large part to nuclear weapons science here at Los Alamos. National security science, and nuclear weapons science in particular, at Los Alamos National Laboratory have provided a key motivation for the evolution of large-scale scientific computing. Beginning with the Manhattan Project there has been a constant stream of increasingly significant, complex problems in nuclear weapons science whose timely solutions demand larger and faster computers. The relationship between national security science at Los Alamos and the evolution of computing is one of interdependence.
97 MATHEMATICS AND COMPUTING↗
Advanced Energy Storage Life and Health Prognostics (INL) (FY 2012 Annual Progress Report)
The objective of this work is to develop methodologies that will accurately estimate state-of-health (SOH) and remaining useful life (RUL) of electrochemical energy storage devices using both offline and online (i.e., in-situ) techniques through: • A statistically robust offline battery calendar life estimator tool based on both testing and simulation, and • Novel onboard sensor technology for improved online battery diagnostics and prognostics.
25 ENERGY STORAGE↗