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Payne, R. G.

Publications and source records attributed to Payne, R. G..

Mechanical properties of a biodegradable bone regeneration scaffold

Poly (Propylene Fumarate) (PPF), a novel, bulk erosion, biodegradable polymer, has been shown to have osteoconductive effects in vivo when used as a bone regeneration scaffold (Peter, S. J., Suggs, L. J., Yaszemski, M. J., Engel, P. S., and Mikos, A. J., 1999, J. Biomater. Sci. Polym. Ed., 10, pp. 363-373). The material properties of the polymer allow it to be injected into irregularly shaped voids in vivo and provide mechanical stability as well as function as a bone regeneration scaffold. We fabricated a series of biomaterial composites, comprised of varying quantities of PPF, NaCl and beta-tricalcium phosphate (beta-TCP), into the shape of right circular cylinders and tested the mechanical properties in four-point bending and compression. The mean modulus of elasticity in compression (Ec) was 1204.2 MPa (SD 32.2) and the mean modulus of elasticity in bending (Eb) was 1274.7 MPa (SD 125.7). All of the moduli were on the order of magnitude of trabecular bone. Changing the level of NaCl from 20 to 40 percent, by mass, did not decrease Ec and Eb significantly, but did decrease bending and compressive strength significantly. Increasing the beta-TCP from 0.25 g/g PPF to 0.5 g/g PPF increased all of the measured mechanical properties of PPF/NVP composites. These results indicate that this biodegradable polymer composite is an attractive candidate for use as a replacement scaffold for trabecular bone.

NASA Discipline Cell Biology↗

VLBI observations of the Crab nebula pulsar

Observations were made at meter wave-lengths using very long base-line interferometry techniques. At 196.5 MHz no resolution of the pulsar are observed; all the pulse shapes observed with the interferometers are similar to single dish profiles, and all the power pulsates. At 111.5 MHz besides the pulsing power there is always a steady component, presumably due to interstellar scattering. The pulsar is slightly resolved at 111.5 MHz with an apparent angular diameter of 0.07 sec ? 0.01 sec. A 50 percent linear polarization of the time-averaged power is noted at 196.5 MHz; at 111.5 MHz, 20 percent of the total time-averaged power is polarized, 35 percent of the pulsing power is polarized, and the steady component is unpolarized.

Vandenberg, N. R.↗