Engineering topics

Phillips, J. A.

Publications and source records attributed to Phillips, J. A..

7 records

NASA NTRS2006

Analysis of Cell Proliferation in Newt (Pleurodeles waltl) Tissue Regeneration during Spaceflight in Foton M-2

Terrestrial organisms exposed to microgravity during spaceflight expe rience musculoskeletal degeneration. It is still not understood if lo nger-term exposures to microgravity induce degeneration in other tiss ues, and if these effects are also observed in neutrally buoyant aqu atic organisms that may be pre-adapted to mechanical unloading. The " Regeneration" experiment conducted collaboratively between Russian an d US scientists for 16 days in the Russian Foton M-2 spaceflight soug ht to test the hypothesis that microgravity alters the proliferation of cells in regenerating tail tissue of the newt Pleurodeles waltl. Our initial results indicate that we successfUlly delivered the proli feration marker 5-bromo-2'-deoxy Uridine (BrdU) during spaceflight, and that it was incorporated in the nuclei of cells in regenerating tis sues. Cells in spaceflight tail regenerates proliferated at a slight ly slower rate and were more undifferentiated than those in ground sy nchronous controls. In addition, the size of regenerating tails from spaceflight was smaller than synchronous controls. However, onboard temperature recordings show that the temperature in spaceflight was a bout 2 C lower than ground synchronous controls, possibly explaining the observed differences. Additional post-facto ground controls at ma tched temperatures will correctly determine the effects of spaceflig ht on regenerative cell proliferation in the newt.

Almeida, E. A. C.↗

NASA NTRS2006

Development of the Gecko (Pachydactylus turneri) Animal Model during Foton M-2 to Study Comparative Effects of Microgravity in Terrestrial and Aquatic Organisms

Terrestrial organisms exposed to microgravity during spaceflight experience degeneration in bone, muscle, and possibly other tissues that require gravity-mediated mechanical stimulation for normal regenerative growth. In the Gecko experiment aboard Foton M-2, we flew for the first time, five terrestrial Pachydactylus turneri specimens to develop a model of microgravity effects comparable to the newt Pleurodeles waltl, a well-established model organism for spaceflight. These lower vertebrate species have similar body plans and size, are poikilothermic, have tissue regenerative ability, and are adapted to moderate periods of fasting. Furthermore the gecko (Pachydactylus) can also survive prolonged periods without water. In pre-flight control experiments and after a 16-day Foton M-2 spaceflight without food or water, the geckos were recovered and showed no apparent negative health effects. However, detailed analysis of bone mass and architecture by micro Computed Tomography { pCT), showed that both synchronous control and spaceflight animals lost significant amounts of cancellous bone in the distal femur and humerus relative to basal controls. In addition, cell cycle analysis of 30h post-flight liver tissue reveals a shift of DNA content from G2 and S to G1, both in spaceflight and synchronous controls. Together, these results suggest that housing conditions alone induce rapid catabolism of cancellous bone and reduced normal tissue regeneration. Further use of the gecko Puchydactylus turneri as a spaceflight model requires modification of housing conditions, possibly by including water and food, or changing other factors such as eliminating housing stresses to obtain stable bone structure and tissue regeneration during spaceflight experiments.

Almeida, E. A.↗

NASA NTRS1993

Planets around pulsars; Proceedings of the Conference, California Inst. of Technology, Pasadena, Apr. 30-May 1, 1992

Topics addressed include planets and pulsar timing; timing noise in pulsars and alternative explanations; orbital dynamics; planet formation scenarios; searches for disks and other planets; and comets, planetesimals, and debris disks. Particular attention is given to PSR 1257+12 and its planetary companions; the detectability of planetary companions to radio pulsars; orbital dynamics of PSR 1257+12 and its two planetary companions; formation and evolution of pulsars; the circumstellar environment of the GG Tau multiple system; IRAS sources near positions of pulsars; and gamma-ray bursts from planetesimal accretion.

Phillips, J. A.↗

NASA NTRS1989

Earth-based observations of Faraday rotation in radio bursts from Jupiter

New observations have been made of Faraday rotation in decameter-wavelength radio bursts from the planet Jupiter. Data obtained during six Io-B storms clearly indicate that an appreciable fraction of the observed Faraday rotation occurs in the Jovian magnetosphere. All of the Faraday rotation observed during a single Io-A storm can be accounted for by earth's ionosphere. Measurements of the Faraday effect in Io-B emissions indicate that the source is in Jupiter's northern magnetic hemisphere. Observations of the Faraday effect in Io-C emissions are proposed to determine its location as well.

Phillips, J. A.↗

NASA NTRS1987

Cross-polarized interferometry of a Jovian decametric radio storm

Observations of an 18-MHz Io-A storm have been conducted using a 46 km cross-polarized interferometer at the University of Florida. The pre- and postdetection correlation properties of LH and RH elliptically polarized L bursts have been studied. Fringe visibility measurements suggest that two discrete and independent sources are sometimes simultaneously active, the polarization sense of one being LH and that of the other RH. A scintillation analysis supports the conclusion that two or more sources were active in such cases.

Phillips, J. A.↗

NASA NTRS1987

18 MHz interferometry of Non-Io-C L-bursts

In order to investigate previous discrepancies in source size measurements, 18-MHz interferometric data of L-bursts from a Non-Io-C storm have been collected during the summer of 1986. Variations noted in the fringe visibility of the Jovian L-bursts indicate that the source size changes in time and that the emission region can sometimes be resolved with a relatively modest baseline. The results suggest that all Jovian source sizes are smaller than 10 arcsec (and are possibly smaller than 0.1 arcmin) and that it is more probable that L-burst emission during a Jovian storm will evolve into S-bursts than that S-bursts will become L-bursts.

Phillips, J. A.↗

NASA NTRS1970

Filler-wire positioner for electron beam welding

Miniaturized positioner is installed in any electron beam vacuum chamber for use with wire feed applications requiring filler wire. Horizontal and vertical control of the positioner is maintained from a console while chamber is under vacuum. Device permits more positive positioning of welding filler wire.

Beaupre, W. M.↗