Engineering topics

Rask, Jon

Publications and source records attributed to Rask, Jon.

8 records

NASA NTRS2019

The NASA Space Life Sciences Training Program: Accomplishments Since 2013

The NASA Space Life Sciences Training Program (SLSTP) provides undergraduate students entering their junior or senior years with professional experience in space life science disciplines. This challenging ten-week summer program is held at NASA Ames Research Center. The primary goal of the program is to train the next generation of scientists and engineers, enabling NASA to meet future research and development challenges in the space life sciences. Students work closely with NASA scientists and engineers on cutting-edge research and technology development. In addition to conducting hands-on research and presenting their findings, SLSTP students attend technical lectures given by experts on a wide range of topics, tour NASA research facilities, participate in leadership and team building exercises, and complete a group project. For this presentation, we will highlight program processes, student recruitment, accomplishments, goals, and feedback from alumni and mentors since 2013. To date, 71 students from 53 different academic institutions, 13 staffers, and 29 mentors have participated in the program.The SLSTP is funded by Space Biology, which is part of the Space Life and Physical Sciences Research and Application division of NASA's Human Exploration and Operations Mission Directorate. The SLSTP is managed by the Space Biology Project within the Science Directorate at Ames Research Center.

Rask, Jon↗

NASA NTRS2017

The NASA Space Life Sciences Training Program: Accomplishments Since 2013

The NASA Space Life Sciences Training Program (SLSTP) provides undergraduate students entering their junior or senior years with professional experience in space life science disciplines. This challenging ten-week summer program is held at NASA Ames Research Center. The primary goal of the program is to train the next generation of scientists and engineers, enabling NASA to meet future research and development challenges in the space life sciences. Students work closely with NASA scientists and engineers on cutting-edge research and technology development. In addition to conducting hands-on research and presenting their findings, SLSTP students attend technical lectures given by experts on a wide range of topics, tour NASA research facilities, participate in leadership and team building exercises, and complete a group project. For this presentation, we will highlight program processes, accomplishments, goals, and feedback from alumni and mentors since 2013. To date, 49 students from 41 different academic institutions, 9 staffers, and 21 mentors have participated in the program. The SLSTP is funded by Space Biology, which is part of the Space Life and Physical Sciences Research and Application division of NASA's Human Exploration and Operations Mission Directorate. The SLSTP is managed by the Space Biology Project within the Science Directorate at Ames Research Center.

education↗

NASA NTRS2017

The NASA Ames Life Sciences Data Archive: Biobanking for the Final Frontier

The NASA Ames Institutional Scientific Collection involves the Ames Life Sciences Data Archive (ALSDA) and a biospecimen repository, which are responsible for archiving information and non-human biospecimens collected from spaceflight and matching ground control experiments. The ALSDA also manages a biospecimen sharing program, performs curation and long-term storage operations, and facilitates distribution of biospecimens for research purposes via a public website (https:lsda.jsc.nasa.gov). As part of our best practices, a tissue viability testing plan has been developed for the repository, which will assess the quality of samples subjected to long-term storage. We expect that the test results will confirm usability of the samples, enable broader science community interest, and verify operational efficiency of the archives. This work will also support NASA open science initiatives and guides development of NASA directives and policy for curation of biological collections.

Biobank↗

NASA NTRS2016

Biospecimen Culling: Temporal RNA Integrity Analysis Across Spaceflight Missions Dating from 1985 to 2011

The Ames Life Science Data Archive (ALSDA) at NASA Ames Research Center is managed by the Space Biosciences Division and has been operational since 1993. The ALSDA is responsible for archiving information and biospecimens collected from life science spaceflight experiments and matching ground control experiments. They are stored in the Ames biobank, which is located in the Biospecimen Storage Facility (BSF). The ALSDA also manages a Biospecimen Sharing Program, performs curation and long-term storage operations, and makes biospecimens available to the scientific community for research purposes via the Life Science Data Archive public website (https:lsda.jsc.nasa.gov). The BSF maintains both fixed and frozen spaceflight and ground tissues, collected from recent and past spaceflight missions. Due to the ever increasing demand for space to preserve current and future flight biospecimens, the ALSDA has initiated the development of a culling plan for biospecimens currently stored in the BSF. Culling enables the ALSDA to assess the quality of archived samples, and supports the development of standardized culling procedures that improve the operational efficiency of the BSF. The culling plan focuses on generating disposition recommendations for samples in the BSF, and currently is based on measuring ribonucleic acid (RNA) integrity number (RIN). The culling process includes (1) sorting and identification of candidate samples for RIN analysis, (2) completion of RIN analysis on select samples, and (3) development of disposition recommendations for specimens based on the RIN values. Furthermore, our approach allows for unique scientific opportunities, including development of a RIN-based methodology for culling, and temporal assessment of the quality of the tissues that have been stored in BSF since the 1980s. Results of this work will also support NASA open science initiatives.

biospecimen↗

NASA NTRS2016

Conceptual Model of Autonomous Seed Germination Habitat for Mars Mission

As human space exploration extends to Mars, the ability to germinate seeds in extraterrestrial environments is becoming a necessity. Recent technological feats such as the development of the European Modular Cultivation System (EMCS) have made botany experiments possible on the International Space Station (ISS). Despite preliminary designs, a biocompatible plant life support system capable of traveling to Mars has yet to be developed. This study focuses on two preparatory measures regarding seed germination in spaceflight: analysis of seed dormancy protocols and compact autonomous habitat development.The objective of this project is to conceptualize a habitat capable of preserving arabidopsis plant seeds on a long duration spaceflight for the purpose of germinating the first plants on Mars. The proposed container will require a compact, low wattage system to provide gas ventilation, artificial light, and water. A visualization system will also need to be developed in order to monitor seed germination remotely. In order to test the effects of dormancy durations on plant viability, we will conduct a ground study to monitor seed germination in seeds which have been dormant for three, six, nine, and twelve months. We will also compare the effects of different sterilization procedures. The results of this study will be instrumental in developing a viable procedure for transferring the first living plants to Mars.

Peter, Jonah↗

NASA NTRS2014

NASA GeneLab Concept of Operations

NASA's GeneLab aims to greatly increase the number of scientists that are using data from space biology investigations on board ISS, emphasizing a systems biology approach to the science. When completed, GeneLab will provide the integrated software and hardware infrastructure, analytical tools and reference datasets for an assortment of model organisms. GeneLab will also provide an environment for scientists to collaborate thereby increasing the possibility for data to be reused for future experimentation. To maximize the value of data from life science experiments performed in space and to make the most advantageous use of the remaining ISS research window, GeneLab will apply an open access approach to conducting spaceflight experiments by generating, and sharing the datasets derived from these biological studies in space.Onboard the ISS, a wide variety of model organisms will be studied and returned to Earth for analysis. Laboratories on the ground will analyze these samples and provide genomic, transcriptomic, metabolomic and proteomic data. Upon receipt, NASA will conduct data quality control tasks and format raw data returned from the omics centers into standardized, annotated information sets that can be readily searched and linked to spaceflight metadata. Once prepared, the biological datasets, as well as any analysis completed, will be made public through the GeneLab Space Bioinformatics System webb as edportal. These efforts will support a collaborative research environment for spaceflight studies that will closely resemble environments created by the Department of Energy (DOE), National Center for Biotechnology Information (NCBI), and other institutions in additional areas of study, such as cancer and environmental biology. The results will allow for comparative analyses that will help scientists around the world take a major leap forward in understanding the effect of microgravity, radiation, and other aspects of the space environment on model organisms. These efforts will speed the process of scientific sharing, iteration, and discovery.

Space Life Science↗

NASA NTRS2013

The Sample Handling System for the Mars Icebreaker Life Mission: from Dirt to Data

The Mars icebreaker life mission will search for subsurface life on mars. It consists of three payload elements: a drill to retrieve soil samples from approx. 1 meter below the surface, a robotic sample handling system to deliver the sample from the drill to the instruments, and the instruments themselves. This paper will discuss the robotic sample handling system.

Martian Arctic↗

NASA NTRS2005

Methods for the culture of C. elegans and S. cerevisiae in microgravity

To support the study of the effects of microgravity on biological systems, our group is developing and testing methods that allow the cultivation of C. elegans and S. cerevisiae in microgravity. Our aim is to develop the experimental means by which investigators may conduct peer reviewed biological experiments with C. elegans or S. cerevisiae in microgravity. Our protocols are aimed at enabling investigators to grow these organisms for extended periods during which samples may be sub-cultured, collected, preserved, frozen, and/or returned to earth for analysis. Data presented include characterization of the growth phenotype of these organisms in liquid medium in OptiCells(TM) (Biocrystal, LTD).

NASA Center ARC↗