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Rowell, L. B.

Publications and source records attributed to Rowell, L. B..

Temperature control system for water-perfused suits

A system used to control skin temperature in human subjects wearing water-perfused garments is described. It supplies 8 l/min at 10 psi with water temperature controlled within plus or minus 0.1 C. Temperature control is facilitated by a low circulating thermal mass and a fast responding heater based on a commercially available quartz heat lamp. The system is open so that hot or cold water can be added from the building mains to produce rates of change of water temperature exceeding 5 C/min. These capabilities allow semiautomatic control of skin temperature within plus or minus 0.1 C of desired wave forms.

Brengelmann, G. L.↗

Use of dew-point detection for quantitative measurement of sweating rate

A method of measuring sweat rate (SR) based on detection of dew point (DP) is proposed which has advantages that may be attractive to other laboratories concerned with recording SR from selected areas of skin. It is similar to other methods in that dry gas is passed through a capsule which isolates several square centimeters of skin surface. The difference is in the means of determining how much gaseous water is carried off in the effluent moist gas. The DP detector used is free of the drawbacks of previous devices. DP is obtained through the fundamental technique of determining the temperature at which condensate forms on a mirror. Variations in DP are tracked rapidly, and accurately (+ or - 0.8 C nominal, sensitivity + or - 0.05 C) over a wide range ( -40 C to +50 C) without measurable hysteresis. The detector asembly is rugged and readily opened for cleaning and inspection.

Brengelmann, G. L.↗

Control of skin blood flow, sweating, and heart rate - Role of skin vs. core temperature

A study was conducted to generate quantitative expressions for the influence of core temperature, skin temperature, and the rate of change of skin temperature on sweat rate, skin blood flow, and heart rate. A second goal of the study was to determine whether the use of esophageal temperature rather than the right atrial temperature as a measure of core temperature would lead to different conclusions about the control of measured effector variables.

Wyss, C. R.↗

Competition between cutaneous vasodilator and vasoconstrictor reflexes in man

A two-part experiment was carried out on seven men to determine whether skin will respond to increased neurogenic vasoconstrictor activity during heating. The latter was induced by lower body negative pressure of -50 mm Hg applied for 5 of each 15 min in 12 studies with constant, neutral skin temperature (32.2-34.4 C) in a 40-min control period and with skin temperature held at 38 C for 40-70 min. We conclude that during heating, skin retains the ability to vasoconstrict but that this vasoconstriction cannot completely override heat-induced vasodilatation.

Johnson, J. M.↗

Skin and muscle components of forearm blood flow in directly heated resting man.

Changes in forearm muscle blood flow (FMBF) during direct whole-body heating were measured in 17 normal subjects using three different methods. We conclude that FMBF is not increased by direct whole-body heating. Since renal and splanchnic blood flow fall 30% under these conditions, maximal total skin blood flow in 12 previously studied subjects can be estimated from the rise in cardiac output to be 7.6 L/min (3.0-11.1 L/min).

Detry, J.-M. R.↗

Importance of the splanchnic vascular bed in human blood pressure regulation.

Three-part experiment in which five subjects were exposed to lower body negative pressure (LBNP) at -50 mm Hg below the iliac crests. Duration of LBNP to earliest vagal symptoms was 7 to 21 min; all data are expressed as changes from control period to the last measurements before these symptoms. In part I, forearm blood flow (by Whitney gauge) fell 45% during LBNP. In part II, splanchnic blood flow (from arterial clearance hepatic extraction of indocyanine green) fell 32% and splanchnic vascular resistance rose 30%. In part III, cardiac output fell 28%, stroke volume 51%, and central blood volume 21%. Total peripheral resistance and heart rate rose 19% and 52%. Of the reduction in total vascular conductance, decreased splanchnic conductance accounted for approximately 33%; skin plus muscle conductance decreased similarly.

Rowell, L. B.↗

Splanchnic vasoconstriction in hyperthermic man - Role of falling blood pressure.

Results of a study in which six supine resting subjects, wearing water-perfused suits, had body skin temperature controlled at 35 C for 30 min (control period), then rapidly increased to 40.5 C for 43 to 50 min (heating period) in a two-part experiment. In the first part of the experiment arterial mean pressure (MP) in three men was increased back to, or above control levels at the 30 to 35th min of heating by total occlusion of both legs for 8 to 10 min. Splanchnic blood flow (SBF), which had fallen from 1.4 to 0.9 L/min at occlusion, rose only 0.05 L/min during occlusion. Splanchnic vascular resistance (SVR) rose throughout heating and occlusion. In the second part of the experiment (three men) SBF fell despite a spontaneous rise in MP and aortic pulse pressure prior to leg occlusion. Cardiac output (CO) was measured just before, during and after occlusion. Occlusion raised MP 10 to 15 mm Hg and reduced CO only slightly. It is concluded that falling MP or aortic pulse pressure are not major causes of the splanchnic vasoconstriction in response to heating man.

Rowell, L. B.↗