Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization
Abstract not provided
Sun, Siyang↗
Engineering topics
Sun, Siyang
Publications and source records attributed to Sun, Siyang.
High processivity polymerases
Chimeric proteins comprising a sequence nonspecific single-stranded nucleic-acid-binding domain joined to a catalytic nucleic-acid-modifying domain are provided. Methods comprising contacting a nucleic acid molecule with a chimeric protein, as well as systems comprising a nucleic acid molecule, a chimeric protein, and an aqueous solution are also provided. The joining of sequence nonspecific single-stranded nucleic-acid-binding domain and a catalytic nucleic-acid-modifying domain in chimeric proteins, among other things, may prevent the separation of the two domains due to their weak association and thereby enhances processivity while maintaining fidelity.
59 BASIC BIOLOGICAL SCIENCES↗