Engineering topics

Tang, Xiaochen

Publications and source records attributed to Tang, Xiaochen.

18 records

DOE OSTI2025

Secondhand Exposure to Simulated Cannabis Vaping Aerosols

Emissions from cannabis vaping degrade indoor air quality and expose non-users to secondhand pollutants. We investigated how the vaping mixture composition affects indoor aerosol characteristics and exposures. Simulated cannabis vaping aerosol was produced by flash evaporation in a 20 m3 chamber of mixtures containing terpenoids, cannabinoids, cannabis extract constituents, and the adulterant vitamin E acetate (VEA). Aerosol time- and size-resolved concentrations (8 nm-2.5 μm at 1 Hz) were measured, and a dosimetry model was used to evaluate the intake of secondhand aerosols. The results showed peak particle number (PN) concentrations between 0.7 × 106 and 13 × 106 cm-3 and peak mass concentration (PM1.0) between 65 and 1191 μg m-3 at t = 5 min after emission. Concentrations decreased to 21-57% of peak PN and 33-69% of peak PM1.0 at t = 60 min. The PM1.0 yield was 0.06 for a terpenoid-only mixture, 0.22-0.36 for tetrahydrocannabinol (THC)-terpenoid mixtures, and >1 for mixtures containing high concentrations of cannabidiol (CBD) or VEA. For intake deposition, the highest aerosol fraction was deposited in the pulmonary region, followed by the tracheobronchial and head regions. Deposition increased in the presence of THC, CBD, or VEA, with aerosols <100 nm contributing the majority of particles deposited in all regions.

Tang, Xiaochen↗

DOE OSTI2024

Air pollutant exposure concentrations from cooking a meal with a gas or induction cooktop and the effectiveness of two recirculating range hoods with filters

Not Available

Li, Jiayu↗

DOE OSTI2024

Inhalation of Trace Metals in Secondhand and Thirdhand Tobacco Smoke Can Result in Increased Health Risks

Here, the presence of toxic metals in tobacco smoke is well documented. However, few studies have quantified trace metals in secondhand smoke (SHS) and thirdhand smoke (THS). Their presence in indoor air can contribute to nonsmokers’ exposures and health effects. In this study, emission and deposition rates of toxic trace metals were determined, and their airborne concentration in typical indoor scenarios was predicted. PM 2.5 was collected on Teflon-coated filters at various times following a smoking event in a room-sized chamber over a 43 h period. The concentration of 28 trace metals was determined by extraction and analysis using inductively coupled plasma-triple quadrupole-mass spectrometry (ICP-QQQ-MS). Emission and indoor deposition rates of cadmium, arsenic, chromium, manganese, beryllium and selenium were determined, and used to predict concentrations expected in a smokers’ home and a smoking bar. In most of the considered scenarios, average indoor concentrations of Cd, As, and Cr exceeded their corresponding cancer risk thresholds and, in some cases, also noncancer reference exposure levels, more than 3 h after smoking ended. The fraction of cadmium that remained airborne was significantly higher than those of other metal traces and that of PM 2.5 , suggesting an association of Cd traces with small particles.

60 APPLIED LIFE SCIENCES↗

DOE OSTI2023

Functional composites by programming entropy-driven nanosheet growth

Here, nanomaterials must be systematically designed to be technologically viable. Driven by optimizing intermolecular interactions, current designs are too rigid to plug in new chemical functionalities and cannot mitigate condition differences during integration. Despite extensive optimization of building blocks and treatments, accessing nanostructures with the required feature sizes and chemistries is difficult. Programming their growth across the nano-to-macro hierarchy also remains challenging, if not impossible. To address these limitations, we should shift to entropy-driven assemblies to gain design flexibility, as seen in high-entropy alloys, and program nanomaterial growth to kinetically match target feature sizes to the mobility of the system during processing. In tis report, following a micro-then-nano growth sequence in ternary composite blends composed of block-copolymer-based supramolecules, small molecules and nanoparticles, we successfully fabricate high-performance barrier materials composed of more than 200 stacked nanosheets (125 nm sheet thickness) with a defect density less than 0.056 µm -2 and about 98% efficiency in controlling the defect type. Contrary to common perception, polymer-chain entanglements are advantageous to realize long-range order, accelerate the fabrication process (<30 min) and satisfy specific requirements to advance multilayered film technology. This study showcases the feasibility, necessity and unlimited opportunities to transform laboratory nanoscience into nanotechnology through systems engineering of self-assembly.

42 ENGINEERING↗

DOE OSTI2023

Policy-relevant differences between secondhand and thirdhand smoke: strengthening protections from involuntary exposure to tobacco smoke pollutants

Starting in the 1970s, individuals, businesses and the public have increasingly benefited from policies prohibiting smoking indoors, saving thousands of lives and billions of dollars in healthcare expenditures. Smokefree policies to protect against secondhand smoke exposure, however, do not fully protect the public from the persistent and toxic chemical residues from tobacco smoke (also known as thirdhand smoke) that linger in indoor environments for years after smoking stops. Nor do these policies address the economic costs that individuals, businesses and the public bear in their attempts to remediate this toxic residue. We discuss policy-relevant differences between secondhand smoke and thirdhand smoke exposure: persistent pollutant reservoirs, pollutant transport, routes of exposure, the time gap between initial cause and effect, and remediation and disposal. We examine four policy considerations to better protect the public from involuntary exposure to tobacco smoke pollutants from all sources. We call for (a) redefining smokefree as free of tobacco smoke pollutants from secondhandandthirdhand smoke; (b) eliminating exemptions to comprehensive smoking bans; (c) identifying indoor environments with significant thirdhand smoke reservoirs; and (d) remediating thirdhand smoke. We use the case of California as an example of how secondhand smoke-protective laws may be strengthened to encompass thirdhand smoke protections. The health risks and economic costs of thirdhand smoke require that smokefree policies, environmental protections, real estate and rental disclosure policies, tenant protections, and consumer protection laws be strengthened to ensure that the public is fully protected from and informed about the risks of thirdhand smoke exposure.

Public, Environmental & Occupational Health↗

DOE OSTI2023

Fraction of Free-Base Nicotine in Simulated Vaping Aerosol Particles Determined by X-ray Spectroscopies

A new generation of electronic cigarettes is exacerbating the youth vaping epidemic by incorporating additives that increase the acidity of generated aerosols, which facilitate uptake of high nicotine levels. We need to better understand the chemical speciation of vaping aerosols to assess the impact of acidification. Here we used X-ray photoelectron spectroscopy (XPS) and near-edge X-ray absorption fine structure (NEXAFS) spectroscopy to probe the acid-base equilibria of nicotine in hydrated vaping aerosols. Here we show that, unlike the behavior observed in bulk water, nicotine in the core of aqueous particles was partially protonated when the pH of the nebulized solution was 10.4, with a fraction of free-base nicotine (α FB ) of 0.34. Nicotine was further protonated by acidification with equimolar addition of benzoic acid (α FB = 0.17 at pH 6.2). By contrast, the degree of nicotine protonation at the particle surface was significantly lower, with 0.72 < α FB < 0.80 in the same pH range. The presence of propylene glycol and glycerol completely eliminated protonation of nicotine at the surface (α FB = 1) while not affecting significantly its acid-base equilibrium in the particle core. These results provide a better understanding of the role of acidifying additives in vaping aerosols, supporting public health policy interventions.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2021

Volatile aldehyde emissions from “sub-ohm” vaping devices

"Sub-ohm" atomizers with reduced resistance can deliver more power than conventional electronic cigarettes. Typical battery outputs are 100 watts or more. These devices are particularly popular among young users, and can be a significant source of volatile carbonyls in the indoor environment. Emissions from next-generation sub-ohm vaping products were characterized by determining e-liquid consumption and volatile aldehydes emissions for several combinations of popular high-power configurations. Tests explored the effect of dilution air flow (air vent opening), puffing volume, and coil assembly configuration. The mass of liquid consumed per puff increased as the puff volume increased from 50 to 100 mL, then remained relatively constant for larger puff volumes up to 500 mL. This is likely due to mass transfer limitations at the wick and coil assembly, which reduced the vaporization rate at higher puff volumes. Carbonyl emission rates were systematically evaluated using a 0.15 Ω dual coil atomizer as a function of the puffing volume and dilution air flow, adjusted by setting the air vents to either 100% (fully open), 50%, 25%, or 0% (closed). The highest formaldehyde emissions were observed for the lowest puff volume (50 mL) when the vents 31 were closed (48 ng mg-1), opened at 25% (39 ng mg -1 ) and at 50% (32 ng mg -1 ).. By contrast, 50-mL puffs with 100% open vents, and puff volumes >100 mL for any vent aperture, generated formaldehyde yields of 20 ng mg -1 or lower, suggesting that a significant cooling effect resulted in limited carbonyl formation. Considering the effect of the coil resistance when operated at a voltage of 3.8 V, the amount of liquid evaporated per puff decreased as the resistance increased, in the order of 0.15 Ω > 0.25 Ω > 0.6 Ω consistent with decreasing aerosol temperatures measured at the mouthpiece. Three different configurations of 0.15 Ω coils (dual, quadruple and octuple) were evaluated, observing significant variability. No clear trend was found between carbonyl emission rates and coil resistance or configuration, with highest emissions corresponding to a 0.25 Ω dual coil atomizer. Carbonyl emission rates were compared with those determined using the same methodology for conventional e-cigarettes (lower power tank systems), observing overall lower yields for the sub-ohm devices.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2021

Emissions from Heated Terpenoids Present in Vaporizable Cannabis Concentrates

Vaporizable cannabis concentrates (VCCs) consumed as a liquid (vaping) or a waxy solid (dabbing) are becoming increasingly popular. However, their associated emissions and impacts have not been fully described. Mixtures containing different proportions of 12 VCC terpenoids and high MW compounds were heated at 100-500 °C inside a room-sized chamber to simulate emissions. Terpenoids, thermal degradation byproducts, and ultrafine particles (UFPs) were quantified in the chamber air. Air samples contained over 50% of emitted monoterpenes and less than 40% of released sesquiterpenes and terpene alcohols. Eleven degradation byproducts were quantified, including acrolein (1.3-3.9 μg m -3 ) and methacrolein (2.0 μg m -3 ). A large amount of UFPs were released upon heating and remained airborne for at least 3 h. The mode diameter increased from 80 nm at 100 °C to 140 nm at 500 °C, and particles smaller than 250 nm contributed to 90% of PM 1.0 . Here, the presence of 0.5% of lignin, flavonoid, and triterpene additives in the heated mixtures resulted in a threefold increase in the particle formation rate and PM 1.0 concentration, suggesting that these high-molecular-weight compounds enhanced aerosol inception and growth. Predicted UFP emission rates in typical consumption scenarios (6 × 10 11 -2 × 10 13 # min -1 ) were higher than, or comparable with, other common indoor sources such as smoking and cooking.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2020

Chemical changes in thirdhand smoke associated with remediation using an ozone generator

Ozonation is a common remediation approach to eliminate odors from mold, tobacco and fire damage in buildings. Little information exists to: 1) assess its effectiveness; 2) provide guidance on operation conditions; and 3) identify potential risks associated with the presence of indoor ozone and ozonation byproducts. The goal of this study is to evaluate chemical changes in thirdhand smoke (THS) aerosols induced by high levels of ozone, in comparison with THS aerosols aged under similar conditions in the absence of ozone. Samples representing different stages of smoke aging in the absence of ozone, including freshly emitted secondhand smoke (SHS) and THS, were collected inside an 18-m 3 room-sized chamber over a period of 42 h after six cigarettes were consumed. The experiments involved collection and analysis of gas phase species including volatile organic compounds (VOCs), volatile carbonyls, semivolatile organic compounds (SVOCs), and particulate matter. VOC analysis was carried out by gas chromatography/mass spectrometry with a thermal desorption inlet (TD-GC/MS), and volatile carbonyls were analyzed by on-line derivatization with dinitrophenylhydrazine (DNPH), followed by liquid chromatography with UV/VIS detection. SVOCs were extracted from XAD-coated denuders and Teflon-coated fiberglass filters in the absence of ozone. In those extracts, tobacco-specific nitrosamines (TSNAs) and other SVOCs were analyzed by gas chromatography with positive chemical ionization-triple quadrupole mass spectrometric detection (GC/PCI-QQQ-MS), and polycyclic aromatic hydrocarbons (PAHs) were quantified by gas chromatography with ion trap mass spectrometric detection (GC/IT-MS) in selected ion monitoring mode. Particulate matter concentration was determined gravimetrically. In a second experiment, a 300 mg h -1 commercial ozone generator was operated during 1 h, one day after smoke was generated, to evaluate the remediation of THS by ozonation. VOCs and volatile carbonyls were analyzed before and after ozonation. Extracts from fabrics that were exposed in the chamber before and after ozonation as surrogates for indoor furnishings were analyzed by GC/IT-MS, and aerosol size distribution was studied with a scanning mobility particle sizer. Ozone concentration was measured with a photometric detector. An estimated 175 mg ozone reacted with THS after 1 h of treatment, corresponding to 58% of the total O 3 released during that period. Fabric-bound nicotine was depleted after ozonation, and the surface concentration of PAHs adsorbed to fabric specimens decreased by an order of magnitude due to reaction with ozone, reaching pre-smoking levels. These results suggest that ozonation has the potential to remove harmful THS chemicals from indoor surfaces. However, gas phase concentrations of volatile carbonyls, including formaldehyde, acetaldehyde and acetone were higher immediately after ozonation. Ultrafine particles (UFP, in most cases with size <60 nm) were a major ozonation byproduct. UFP number concentrations peaked shortly after ozonation ended, and remained at higher-than background levels for several hours. Based on these results, minimum re-entry times after ozone treatment were predicted for different indoor scenarios. Clearly defining re-entry times can serve as a practical measure to prevent acute exposures to ozone and harmful ozonation byproducts after treatment. This study evaluated potential benefits and risks associated with THS remediation using ozone, providing insights into this technology.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2020

Self-cleaning and de-pollution efficacies of photocatalytic architectural membranes

Photocatalytic self-cleaning “cool” roofs and walls can maintain high albedos, saving building cooling energy, reducing peak power demand, and mitigating the urban heat island effect. Other environmental benefits result from their de-polluting properties. Specimens from two different photocatalytic architectural membranes and a non-photocatalytic control were exposed alongside vertically, facing west, for two years at three California sites, and retrieved quarterly for testing. Photocatalytic materials showed excellent self-cleaning performance, retaining albedos of 0.74 – 0.75. By contrast, the control material exhibited an albedo loss of up to 0.10, with appreciable soiling observed by scanning electron microscopy. De-pollution capacity was assessed by quantifying NO removal and NOx deposition rates at 60 °C. Furthermore, efficacy varied with exposure location, weather conditions, and the nature of the photocatalytic material. Seasonal effects were observed, with partial inhibition during the dry season and reactivation during the rainy season.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2020

Performance of a CO 2 sorbent for indoor air cleaning applications: Effects of environmental conditions, sorbent aging, and adsorption of co-occurring formaldehyde

Indoor air cleaning systems that incorporate CO 2 sorbent materials enable HVAC load shifting and efficiency improvements. This study developed a bench-scale experimental system to evaluate the performance of a sorbent under controlled operation conditions. A thermostatic holder containing 3.15 g sorbent was connected to a manifold that delivered CO 2 -enriched air at a known temperature and relative humidity (RH). The air stream was also enriched with 0.8-2.1 ppm formaldehyde. The CO 2 concentration was monitored in real-time upstream and downstream of the sorbent, and integrated formaldehyde samples were collected at different times using DNPH-coated silica cartridges. Sorbent regeneration was carried out by circulating clean air in countercurrent. Almost 200 loading/regeneration cycles were performed in the span of 17 months, from which 104 were carried out at reference test conditions defined by loading with air at 25°C, 38% RH, and 1000 ppm CO 2 , and regenerating with air at 80°C, 3% RH and 400 ppm CO 2 . The working capacity decreased slightly from 43-44 mg CO 2 per g sorbent to 39-40 mg per g over the 17 months. The capacity increased with lower loading temperature (in the range 15-35°C) and higher regeneration temperature, between 40 and 80°C. The CO 2 capacity was not sensitive to the moisture content in the range 6-9 g/m 3 , and decreased slightly when dry air was used. Loading isothermal breakthrough curves were fitted to three simple adsorption models, verifying that pseudo-first-order kinetics appropriately describes the adsorption process. The model predicted that equilibrium capacities decreased with increasing temperature from 15 to 35°C, while adsorption rate constants slightly increased. The formaldehyde adsorption efficiency was 80%-99% in different cycles, corresponding to an average capacity of 86 ± 36 µg/g. Formaldehyde was not quantitatively released during regeneration, but its accumulation on the sorbent did not affect CO 2 adsorption.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

DOE OSTI2020

Evaluation of short-term initial performance of a “Molekule Air” portable air cleaner

The aim of this project was to evaluate and characterize the performance of a MOLEKULE AIR air cleaner unit. The testing protocol comprised the evaluation of an unused Molekule Air unit operating at maximum (“boost” setting) fan speed setting. The device was tested over initial short-term periods of 70-80 h of continuous operation. The tested air cleaner was challenged in separate experiments with a well-characterized mixture of volatile organic compounds (VOCs), and with ozone. All tests were performed at realistic pollutant levels in a 20-m 3 environmental stainless-steel chamber. Variables controlled and measured in this study included the chamber temperature, relative humidity, the composition and concentration of the challenge VOCs, and the concentrations of ozone. Potential formation of byproducts was also investigated to assess the overall performance.

47 OTHER INSTRUMENTATION↗

DOE OSTI2019

Heated Tobacco Products: Volatile Emissions and Their Predicted Impact on Indoor Air Quality

This study characterized emissions from IQOS, a heated tobacco product promoted as a less harmful alternative to cigarettes. Consumable tobacco plugs were analyzed by headspace GC/MS to assess the influence of heating temperature on the emission profile. Yields of major chemical constituents increased from 4.1 mg per unit at 180 °C to 6.2 mg at 200 °C, and 10.5 mg at 220 °C. The Health Canada Intense smoking regime was used to operate IQOS in an environmental chamber, quantifying 33 volatile organic compounds in mainstream and sidestream emissions. Aldehydes, nitrogenated species, and aromatic species were found, along with other harmful and potentially harmful compounds. Compared with combustion cigarettes, IQOS yields were in most cases 1-2 orders of magnitude lower. However, yields were closer to, and sometimes higher than electronic cigarettes. Predicted users' daily average intake of benzene, formaldehyde, acetaldehyde and acrolein were 39 μg, 32 μg, 2.2 mg and 71 μg, respectively. Indoor air concentrations were estimated for commonly encountered scenarios, with acrolein levels of concern (over 0.35 μg m-3) derived from IQOS used in homes and public spaces. Heated tobacco products are shown to be a weaker indoor pollution source than conventional cigarettes, but their impacts are neither negligible nor yet fully understood.

54 ENVIRONMENTAL SCIENCES↗

DOE OSTI2019

Solar-Reflective “Cool” Walls: Benefits, Technologies, and Implementation

Raising the albedo (solar reflectance) of a building’s walls reduces unwanted solar heat gain in the cooling season. This saves electricity and lowers peak power demand by decreasing the need for air conditioning. It can also cool the outside air, which can mitigate the urban heat island effect and also improve air quality by slowing the reactions that produce smog. This project quantified the energy savings, peak demand reduction, urban cooling, and air quality improvements attainable from solar-reflective “cool” walls in California; collaborated with industry to assess the performance of existing cool-wall technologies, and to develop innovative cool-wall solutions; and worked with state and federal government agencies, utilities, and industry to create a cool-wall infrastructure, including application guidelines, a product rating program, incentives, and building code credits. Simulations indicate that cool walls provide annual energy savings, peak demand reduction, annual emission reduction, and summer heat island mitigation benefits comparable to those yielded by cool roofs, and are helpful across California and in most of the southern half of the United States (that is, in U.S. climate zones 1—4). Natural exposure trials conducted at three sites in California and another three sites across the United States indicate that cool-wall materials tend to stay clean and reflective. Significant advances were made in novel cool-wall technologies, such as fluorescent cool pigments that expand the color palette for cool-wall products. We prepared guidelines for the climate- and building-appropriate use of cool walls, convened a stakeholder workshop, and created a working group. Ongoing efforts seek to introduce or expand cool-wall provisions in building energy standards, green building programs, and energy efficiency incentive programs, and to develop a cool-wall product rating system.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

DOE OSTI2019

Solar-Reflective “Cool” Walls: Benefits, Technologies, and Implementation

utility incentives↗

DOE OSTI2019

De-pollution efficacy of photocatalytic roofing granules

Photocatalytic building surfaces can harness sunlight to reduce urban air pollution. The NO x abatement capacity of TiO 2 -coated granules used in roofing products was evaluated for commercial product development. A laboratory test chamber and ancillary setup were built following conditions prescribed by ISO Standard 22197-1. It was validated by exposing reference P25-coated aluminum plates to a 3 L min -1 air flow enriched in 1 ppm NO under UVA irradiation (360 nm, 11.5 W m -2 ). We characterized prototype granule-surfaced asphalt shingles and loose granules prepared with different TiO 2 loadings and post-treatment formulations. Tests performed at surface temperatures of 25 and 60 °C showed that NO x abatement was more effective at the higher temperature. Preliminary tests explored the use of 1 ppm NO 2 and of 1 ppm and 0.3 ppm NO/NO 2 mixtures. Specimens were aged in a laboratory accelerated weathering apparatus, and by exposure to the outdoor environment over periods that included dry and rainy seasons. Laboratory aging led to higher NO removal and NO 2 formation rates, and the same catalyst activation was observed after field exposure with frequent precipitation. However, exposure during the dry season reduced the performance. This inactivation was mitigated by cleaning the surface of field-exposed specimens. Doubling the TiO 2 loading led to a 50–150% increase in NO removal and NO x deposition rates. Finally, application of different post-treatment coatings decreased NO removal rates (21–35%) and NO x deposition rates (26–74%) with respect to untreated granules. The mass balance of nitrogenated species was assessed by extracting granules after UV exposure in a 1 ppm NO-enriched atmosphere.

54 ENVIRONMENTAL SCIENCES↗

DOE OSTI2018

Short-term early exposure to thirdhand cigarette smoke increases lung cancer incidence in mice

Exposure to thirdhand smoke (THS) is a recently described health concern that arises in many indoor environments. However, the carcinogenic potential of THS, a critical consideration in risk assessment, remains untested. Here we investigated the effects of short-term early exposure to THS on lung carcinogenesis in A/J mice. Forty weeks after THS exposure from 4 to 7 weeks of age, the mice had increased incidence of lung adenocarcinoma, tumor size and, multiplicity, compared with controls. In vitro studies using cultured human lung cancer cells showed that THS exposure induced DNA double-strand breaks and increased cell proliferation and colony formation. RNA sequencing analysis revealed that THS exposure induced endoplasmic reticulum stress and activated p53 signaling. Activation of the p53 pathway was confirmed by an increase in its targets p21 and BAX. These data indicate that early exposure to THS is associated with increased lung cancer risk.

59 BASIC BIOLOGICAL SCIENCES↗

DOE OSTI2016

Concentrations and Sources of Airborne Particles in a Neonatal Intensive Care Unit

Premature infants in neonatal intensive care units (NICUs) have underdeveloped immune systems, making them susceptible to adverse health consequences from air pollutant exposure. Little is known about the sources of indoor airborne particles that contribute to the exposure of premature infants in the NICU environment. In this study, we monitored the spatial and temporal variations of airborne particulate matter concentrations along with other indoor environmental parameters and human occupancy. The experiments were conducted over one year in a private-style NICU. The NICU was served by a central heating, ventilation and air-conditioning (HVAC) system equipped with an economizer and a high-efficiency particle filtration system. The following parameters were measured continuously during weekdays with 1-min resolution: particles larger than 0.3 μm resolved into 6 size groups, CO 2 level, dry-bulb temperature and relative humidity, and presence or absence of occupants. Altogether, over sixteen periods of a few weeks each, measurements were conducted in rooms occupied with premature infants. In parallel, a second monitoring station was operated in a nearby hallway or at the local nurses’ station. The monitoring data suggest a strong link between indoor particle concentrations and human occupancy. Detected particle peaks from occupancy were clearly discernible among larger particles and imperceptible for submicron (0.3–1 μm) particles. The mean indoor particle mass concentrations averaged across the size range 0.3–10 μm during occupied periods was 1.9 μg/m 3 , approximately 2.5 times the concentration during unoccupied periods (0.8 μg/m 3 ). Contributions of within-room emissions to total PM10 mass in the baby rooms averaged 37–81%. Near-room indoor emissions and outdoor sources contributed 18–59% and 1–5%, respectively. Airborne particle levels in the size range 1–10 μm showed strong dependence on human activities, indicating the importance of indoor-generated particles for infant’s exposure to airborne particulate matter in the NICU.

60 APPLIED LIFE SCIENCES↗