Design and evaluation of achiral, non-atropisomeric 4-(aminomethyl)phthalazin-1(2H)-one derivatives as novel PRMT5/MTA inhibitors
Not Available
59 BASIC BIOLOGICAL SCIENCES↗
Engineering topics
Waters, Laura M.
Publications and source records attributed to Waters, Laura M..
Requirements and concept for an on-orbit construction facility for phase 1 Space Station Freedom
A construction facility attached to NASA's Space Station Freedom (SSF) will be required for the accommodation of assembly activities for large payloads, as well as demonstration of the on-orbit construction of future spacecraft. This facility's capabilities must be sufficiently flexible to address the wide variety of future spacecraft needs without compromising the SSF's phase 1 configuration. The proposed construction facility concept will incorporate a storage module, a construction turntable, equipment-attachment platforms, a surrogate payload bay structure, and a portable workstation. Attention is given to this configuration's resulting mass properties and control characteristics.
Buchan, Robert W.↗
Low earth orbit infrastructure to accommodate manned lunar missions
In order to establish bases on the lunar and Mars surfaces, a significant amount of orbital infrastructure including assembly platforms, cryogenic fluids depots, and Space Station Freedom, will be required in LEO. These facilities will be required to perform a myriad of functions ranging from orbital demonstration of advanced technology systems and establishment of life science capabilities to servicing and refurbishment of reusable lunar transfer vehicles. This paper addresses the requirements levied on these facilities and provides an overview of potetial LEO infrastructure elements that satisfy various advanced manned missions. Of key importance to the success of the manned lunar mission are (1) the evolutionary growth of Space Station Freedom to serve as a transportation node and (2) the development of a Shuttle-derived launch vehicle to deliver mission elements to LEO.
Cirillo, William M.↗
An evolutionary construction facility for Space Station Freedom
Viewgraphs and discussion on an evolutionary construction facility for Space Station Freedom are presented. Space Station Freedom (SSF) will support permanent human presence in space and has the potential to enable scientific and exploratory endeavors unequalled in history. With larger and more ambitious spacecraft being developed, it will serve as a site for construction, checkout, and deployment. A facility attached to SSF is required to develop and demonstrate the techniques that will enable on-orbit construction of future large spacecraft. Examples of attached scientific experiments that currently envision in-space construction and that are discussed are: Solar X-ray Pinhole Occulter Facility, Astromag, and X-ray Large Array. Examples of large assemblable spacecraft which are discussed are: Large Deployable Reflector (LDR), Geostationary Platforms, and interplanetary vehicles.
Gates, Richard M.↗