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Yang, Xi

Publications and source records attributed to Yang, Xi.

At least 55 records · Page 3

Applying Multi-Frequency AC LOCO for Finding Sextupole Errors

A fast and precise technique of multi-frequency AC LOCO has been developed and tested for finding the sextupole alignment and field-offset errors at NSLS-II. This technique is based on sine-wave beam excitation simultaneously at multiple frequencies via different fast correctors. The unique combination of the fast speed and high measurement accuracy opens the door for two different types of potential applications: finding the sextupole alignment and field-offset errors. Beam excitation via fast correctors results in the elimination of the systematic error caused by the hysteresis effect. Systematic errors of the sextupole alignment caused by orbit drift and power supply calibration are also eliminated because the measurement takes only two minutes and does not depend on the current-to-field conversion of sextupole magnets. Furthermore, the simulation studies indicate that multi-frequency AC LOCO together with an orbit bump bigger than 0.5 mm can be applied to measure the relative field offset of a sextupole magnet with a precision better than 10%. The measurement technique is described and the results of two proof-of-principle experiments carried out at NSLS-II are presented.

43 PARTICLE ACCELERATORS↗

FOFB-compatible AC Local Bump as a Potential New Operations Mode for NSLS-II

AC local bumps of the beam orbit developed at NSLS-II are successfully used for accelerator physics studies. Recently, AC bumps localized at light-generating insertion devices (ID) are considered by NSLS-II beamline scientists as a possible user operation mode. The AC perturbation of the X-ray beam in a controllable way will provide a possibility to investigate the effects of the source size and temporal evolution on the coherence of the photon beam. It also can be used to average out the spatial non-uniformity of the beam intensity caused by the beamline optics. Before the implementation of the AC orbit bumps into user operations, we must investigate if the electron beam perturbation affects the other beamlines. A proof-of-principle experiment was carried out: an AC bump was created and well localized in the CSX and/or FXI beamline. Transparency of this AC bump to other beamlines has been studied, the results are discussed.

36 MATERIALS SCIENCE↗

Recent improvements in beam orbit feedback at NSLS-II

This paper discusses improvements made to the fast orbit feedback (FOFB) system at NSLS-II in 2019. We first characterized the system by measuring the transfer function and the closed-loop gain of the system. We also constructed a model to predict the performance, which was based on physical behaviors. After finding and fixing the sources of the latency, we improved the closed-loop gain’s bandwidth from 250 Hz to 400 Hz in the horizontal plane and 250 Hz to 300 Hz in the vertical plane. As a result, the orbit beam instability improved by 30% and 10% in the horizontal and vertical planes, respectively.

36 MATERIALS SCIENCE↗

Software-Defined Network for End-to-end Networked Science at the Exascale

Domain science applications and workflow processes are currently forced to view the network as an opaque infrastructure into which they inject data and hope that it emerges at the destination with an acceptable Quality of Experience. There is little ability for applications to interact with the network to exchange information, negotiate performance parameters, discover expected performance metrics, or receive status/troubleshooting information in real time. The work we presen here is motivated by a vision for a new smart network and smart application ecosystem that will provide a more deterministic and interactive environment for domain science workflows. The Software-Defined Network for End-to-end Networked Science at Exascale (SENSE) system includes a model-based architecture, implementation, and deployment which enables automated end-to-end network service instantiation across administrative domains. An intent based interface allows applications to express their high-level service requirements, an intelligent orchestrator and resource control systems allow for custom tailoring of scalability and real-time responsiveness based on individual application and infrastructure operator requirements. This allows the science applications to manage the network as a first-class schedulable resource as is the current practice for instruments, compute, and storage systems. Deployment and experiments on production networks and testbeds have validated SENSE functions and performance. Emulation based testing verified the scalability needed to support research and education infrastructures. Key contributions of this work include an architecture definition, reference implementation, and deployment. This provides the basis for further innovation of smart network services to accelerate scientific discovery in the era of big data, cloud computing, machine learning and artificial intelligence.

97 MATHEMATICS AND COMPUTING↗

5G Enabled Energy Innovation: Advanced Wireless Networks for Science (Workshop Report)

Rapidly expanding, new telecommunications infrastructure based on 5G technologies will disrupt and transform how we design, build, operate, and optimize scientific infrastructure and the experiments and services enabled by that infrastructure, from continental-scale sensor networks to centralized scientific user facilities, from intelligent Internet of Things devices to supercomputers. Concurrently, 5G will introduce, or exacerbate, challenges related to protecting infrastructure and associated scientific data as well as to fully leveraging opportunities related to expanded infrastructure scale and complexity. The U.S. Department of Energy (DOE) Office of Science operates scientific infrastructure, supporting some of the nation’s most advanced intellectual discoveries, spanning the country and including 30 world-class user facilities from supercomputers to accelerators. Along with field experiments and remote observatories, every aspect of DOE’s scientific enterprise will be affected by 5G, which amounts to a complete renovation of the underpinnings of the nation’s information infrastructure. In this report we explore the scientific opportunities and new research challenges associated with 5G, ranging from scalability to heterogeneity to cybersecurity. The rapid commercial deployment of 5G opens the opportunity to rethink and reinvent DOE’s scientific infrastructure and experimentation, from intelligent sensor networks at unprecedented scales to a digital continuum of cyberinfrastructure spanning low-power sensors, high-performance computing embedded within and at the edge of the network, and DOE’s large-scale user instrument and computing facilities. New programming paradigms, workflow and data frameworks, and AI-based system design, operation, and autonomous adaptation and optimization will be necessary in order to exploit these new opportunities. Field deployments and centralized scientific instruments can also be revolutionized, moving (without traditional performance penalties) from wired to wireless connectivity for data and control systems, improving flexibility, and opening new sensing modalities, including the use of the 5G electromagnetic spectrum itself as an environmental probe. For DOE science, in contrast to commercial 5G applications and settings, devices will be deployed in extreme environments such as cryogenically cooled instrument control systems and in remote settings with harsh conditions, requiring the design of new materials for RF communication and edge processing to operate in these regimes. Concurrently, 5G infrastructure comprises both hardware and sophisticated software systems - currently closed and proprietary. The cybersecurity challenges to 5G-empowered reinvention mirror the complexity and variety of new 5G features, from virtualization to private network slices to ubiquitous access. Research is also needed in order to accelerate the development of secure and open 5G software infrastructure, reducing reliance on hardware and software produced outside the United States and providing the transparency and rigorous evaluation and testing afforded through open software. Twelve broad research thrusts are laid out in four chapters, with a companion fifth chapter (and three additional research thrusts) underscoring the needs and opportunities for an aggressive testbed program co-designed by networking experts and scientists involved in the 15 research thrusts. The urgency of undertaking this research is fueled by a global, accelerating deployment of new telecommunications infrastructure that is designed for entertainment and commercial applications - barely scratching the surface of what 5G can do to extend U.S. leadership in scientific discovery.

42 ENGINEERING↗

Varying Contributions of Drivers to the Relationship Between Canopy Photosynthesis and Far‐Red Sun‐Induced Fluorescence for Two Maize Sites at Different Temporal Scales

Abstract Sun‐induced fluorescence (SIF) has been found to be strongly correlated with gross primary production (GPP) in a quasi‐linear pattern at the scales beyond leaves. However, the causes of the GPP:SIF relationship deviating from a linear pattern remain unclear. In the current study conducted at two maize sites in Nebraska in 2017 summer growing season, we investigated the relationship between GPP and SIF at 760 nm (F 760 ) at two temporal scales and quantified the contributions of incoming photosynthetically active radiation (PAR in ), fraction of absorbed PAR (fPAR), light use efficiency (LUE), and F 760 yield (F 760,y , defined as F 760 /(PAR in ×fPAR)) to GPP and F 760 variabilities to further understand the linearity and deviations in the GPP:F 760 relationship. We found the following: (1) For individual growth stages when canopy structure and chlorophyll content were stable, GPP and F 760 were strongly controlled by PAR in , while LUE and F 760,y had much lower contributions to the GPP:F 760 relationship; during this period, LUE and F 760,y had either a slightly negative or no clear relationship, which explained some deviations in the GPP:SIF relationship. (2) At the seasonal scale, the contribution of LUE to GPP variability as well as the contribution of F 760,y to F 760 variability increased and was comparable to the contribution of PAR in ; the LUE:F 760,y relationship showed a strong linear relationship, which strengthened the linear GPP:F 760 relationship. Both maize sites showed similar patterns. A framework was applied to estimate LUE at individual stages and as a result, significantly improved the GPP estimation, thus enhancing the SIF potential for inferring photosynthesis.

Miao, Guofang↗

Radiance-based NIR v as a proxy for GPP of corn and soybean

Substantial uncertainty exists in daily and sub-daily gross primary production (GPP) estimation, which dampens accurate monitoring of the global carbon cycle. Here we find that near-infrared radiance of vegetation (NIR v,Rad ), defined as the product of observed NIR radiance and normalized difference vegetation index (NDVI), can accurately estimate corn and soybean GPP at daily and half-hourly time scales, benchmarked with multi-year tower-based GPP at three sites with different environmental and irrigation conditions. Overall, NIR v,Rad explains 84% and 78% variations of half-hourly GPP for corn and soybean, respectively, outperforming NIR reflectance of vegetation (NIR v,Ref ), enhanced vegetation index (EVI), and far-red solar-induced fluorescence (SIF760). The strong linear relationship between NIR v,Rad and absorbed photosynthetically active radiation by green leaves (APAR green ), and that between APAR green and GPP, explain the good NIR v,Rad -GPP relationship. The NIR v,Rad -GPP relationship is robust and consistent across sites. The scalability and simplicity of NIR v,Rad indicate a great potential to estimate daily or sub-daily GPP from high-resolution and/or long-term satellite remote sensing data.

54 ENVIRONMENTAL SCIENCES↗

ROBIN (RuciO/BIgData Express/SENSE) A Next-Generation High-Performance Data Service Platform

Increasingly, scientific research discoverydepends on the analysis of extremely large amounts of data. Thisdata is gathered through very large scientific instruments, verylarge numbers of small devices, and mid-scale instruments.These devices generate exponentially increasing volumes of data.Such data is often obtained, analyzed, stored, visualized, andtransferred at and among sites world-wide by largecollaborations of science communities. Managing and movingextremely large volumes of data across today’s networks is aspecial multidimensional challenge. Also, existing datamanagement and movement services and tools often areinadequate to address all specific requirements. This paperdescribes the various components of this challenge and howthose issues can be addressed by ROBIN, a uniquecomprehensive set of integrated services designed specificallyfor managing and moving extremely large amounts of data overlong distances, e.g., thousands of miles around the globe. Thispaper also describes the results of initial experiments using thatset of integrated services.

Wu, Wenji↗

A novel nondestructive diagnostic method for mega-electron-volt ultrafast electron diffraction

Abstract A real-time, nondestructive, Bragg-diffracted electron beam energy, energy-spread and spatial-pointing jitter monitor is experimentally verified by encoding the electron beam energy and spatial-pointing jitter information into the mega-electron-volt ultrafast electron diffraction pattern. The shot-to-shot fluctuation of the diffraction pattern is then decomposed to two basic modes, i.e., the distance between the Bragg peaks as well as its variation (radial mode) and the overall lateral shift of the whole pattern (drift mode). Since these two modes are completely decoupled, the Bragg-diffraction method can simultaneously measure the shot-to-shot energy fluctuation from the radial mode with 2·10 −4 precision and spatial-pointing jitter from the drift mode having wide measurement span covering energy jitter range from 10 −4 to 10 −1 . The key advantage of this method is that it allows us to extract the electron beam energy spread concurrently with the ongoing experiment and enables online optimization of the electron beam especially for future high charge single-shot ultrafast electron diffraction (UED) and ultrafast electron microscopy (UEM) experiments. Furthermore, real-time energy measurement enables the filtering process to remove off-energy shots, improving the resolution of time-resolved UED. As a result, this method can be applied to the entire UED user community, beyond the traditional electron beam diagnostics of accelerators used by accelerator physicists.

43 PARTICLE ACCELERATORS↗

NSLS-II FOFB Performance Improvement in 2019

APS-U declared that they have achieved 700 Hz to 1kHz fast orbit feedback (FOFB) closeloop bandwidth in their two-section test setup. Before this, most light sources have been running FOFB with 100-200Hz bandwidth. Table 1 shows the information of bandwidths and sampling rates of various Synchrotron facilities.

36 MATERIALS SCIENCE↗

Predicting the Value of Adjuvant Therapy in Esophageal Squamous Cell Carcinoma by Combining the Total Number of Examined Lymph Nodes with the Positive Lymph Node Ratio

Background: The value of adjuvant therapy for esophageal squamous cell carcinoma (ESCC) has been controversial, at least partially due to the lack of efficient criteria for selecting suitable patients. This study aimed to explore the existence of parameters related to lymph node (LN) status that can predict the value of adjuvant therapy in ESCC. Methods: The study included 298 patients with ESCC who had undergone radical esophagectomy with lymphadenectomy. Adjuvant therapy was defined as reception of adjuvant chemotherapy, radiotherapy, or chemoradiotherapy. For the study, LN ratio (LNR), total number of resected LNs (TLNs), and pN stage were selected for Cox regression analyses, including their correlations and prognostic values for survival. Log-rank tests were used to compare the survival rates of the patients with and without adjuvant therapy stratified by pN stage, TLNs, LNR, or their combinations. Results: The independent prognostic factors for survival were TLNs, LNR, and pN stage. Whereas pN stage was significantly related to TLNs and LNR, TLNs were not correlated with LNR. The survival rates between the patients with and those without adjuvant therapy stratified by pN stage, TLNs, or LNR did not differ significantly. We used the median values of TLNs and LNR to group the patients into four groups. The patients in the group with fewer TLNs and higher LNR who had undergone adjuvant therapy showed a significantly better survival than those without adjuvant therapy (p = 0.030). Conclusions: In contrast to TLNs, LNR, and pN stage as single factors, the combination of TLNs and LNR can predict the value of adjuvant therapy.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

A compact tunable quadrupole lens for brighter and sharper ultra-fast electron diffraction imaging

In this article, we report our proof-of-principle design and experimental commissioning of a broadly tunable and low-cost transverse focusing lens system for MeV-energy electron beams. The lens system based on electromagnetic (EM) quadrupoles has been built as a part of the existing instrument for ultra-fast electron diffraction (UED) experiments at the Accelerator Test Facility II (ATF-II) at Brookhaven National Laboratory (BNL). We experimentally demonstrated the independent control of the size and divergence of the beam with the charge ranging from 1 to 13 pC. The charge density and divergence of the beam at the sample are the most important factors determining the quality of the Bragg-diffraction image (BDI). By applying the Robust Conjugate Directional Search (RCDS) algorithm for online optimization of the quadrupoles, the transverse beam size can be kept constant down to 75 µm from 1 to 13 pC. The charge density is nearly two orders of magnitude higher than the previously achieved value using a conventional solenoid. Using the BDI method we were able to extract the divergence of the beam in real-time and apply it to the emittance measurement for the first time. Our results agree well with simulations and with the traditional quadrupole scan method. The real-time divergence measurement opens the possibility of online optimization of the beam divergence (< 0.2 mrad) at the sample with the increased beam charge. This optimization is crucial for the future development of single-shot ultra-fast electron microscope (UEM). Finally, we demonstrated BDI with significant improvement, up to 3 times higher peak intensity and 2 times sharper Bragg-diffraction peaks at 13 pC. The charge is now limited by the laser power and increasing charge may improve the quality of BDI further. The capability we demonstrated here provides us with opportunities for new sciences using near-parallel, bright and ultrafast electron beams for single-shot imaging, to directly visualize the dynamics of defects and nanostructured materials, or even record molecular movie, which are impossible using present electron-beam technologies.

43 PARTICLE ACCELERATORS↗

The role of UNC5b in ox-LDL inhibiting migration of RAW264.7 macrophages and the involvement of CCR7

Highlights: ∙The netrin-1, and its receptor UNC5b, are expressed by macrophage foam cells. ∙The up-regulation of UNC5b and netrin-1 was in respond to ox-LDL in Raw264.7 macrophage, and was associated with decreasing cell migration. ∙In ox-LDL inducement, UNC5b down-regulated CCR7, and then inhibited macrophage migration. The formation of macrophage foam cells by ingesting ox-LDL and focal retention in the subendothelial space are the hallmarks of the early atherosclerotic lesion. The C-C chemokine receptor type 7 (CCR7) is positively correlated with the macrophage migration. But the mechanism of CCR7 regulation is not fully clearness. In the present study, we demonstrates that expression in UNC5b and netrin-1 was enhanced in respond to ox-LDL in Raw264.7 macrophage and associated with decreasing cell migration. Interestingly, it was found that ox-LDL significantly downregulate CCR7 gene expression. The expression of CCR7 in mRNA and protein levels were decreased in ox-LDL treated Raw264.7 macrophage when we over expression of UNC5b with pcDNA3.1-UNC5b plasmid. We got the inverse results after silence UNC5b gene with siUNC5b. Meanwhile, the data show that in ox-LDL inducement, UNC5b down-regulated CCR7, and then inhibited macrophage migration. This novel phenomenon is of a crucial highlights to understand deeply the pathogenesis of atherosclerosis. The molecular mechanism of CCR7 regulation deserves intensive study.

60 APPLIED LIFE SCIENCES↗

Study Results and Plans for Future Improvement of the NSLS-II FOFB System

Currently, the fast orbit feedback (FOFB) system correct the transverse orbit in both planes via air coil magnets installed over low conductivity sections of vacuum chamber (stainless steel bellows) with a fast acquisition (FA) that samples at 10kHz. Bandwidth of a few kHz has been achieved (power-supply + corrector + vacuum chamber) for the purpose that the FOFB bandwidth limitation is not anymore limited by the correctors. The bandwidths of the FOFB system in both planes have been experimentally characterized in the open-loop condition via sinwave excitation method. They are significantly lower than the measurements (2.5kHz in x) done by Weixing Chen et al when the control system was largely bypassed, only from PSI to fast correctors, final to BPM. The estimated dI/dt as a function of the frequency from the beam noise spectrum has been compared to the slew rate of the power supply. The most recent study evidences: after the optimization of fast corrector compensation circuit, the power supply system along shows the 3dB bandwidth of 5.6kHz in the horizontal plane and 3.5kHz in the vertical plane. Preliminary beam studies indicate the potential increase of the system bandwidth and the gain within the FOFB bandwidth. Finally, the plan for combing the FOFB and SOFB systems to correct down to DC has been discussed.

36 MATERIALS SCIENCE↗