TY - RPRT TI - An Integral Activity-Based Protein Profiling Method for Higher Throughput Determination of Protein Target Sensitivity to Small Molecules AU - Kombala, Chathuri Jeewanthi [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] (ORCID:0000000238478769) AU - Sveistyte, Agne [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] AU - Zhang, Tong [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] (ORCID:0000000325402017) AU - Gorham, Leo J. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] (ORCID:0009000113010422) AU - Lomas, Gerard X. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] AU - Melchior, John T. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Univ. of Cincinnati, OH (United States); Oregon Health and Science Univ., Portland, OR (United States)] (ORCID:0000000337812566) AU - Lalli, Priscila M. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] AU - Paurus, Vanessa L. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] (ORCID:0000000289602926) AU - Callister, Stephen J. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] (ORCID:0000000317852755) AU - Wright, Aaron T. [Baylor Univ., Waco, TX (United States)] (ORCID:0000000231725253) AU - Lin, Vivian S. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] (ORCID:0000000191590031) PY - 2025 DO - 10.1021/acschembio.5c00412 UR - https://www.osti.gov/biblio/3004237 ID - 3004237 ER -