TY - RPRT TI - Sequence-based generative AI design of versatile tryptophan synthases AU - Lambert, Théophile [California Institute of Technology (CalTech), Pasadena, CA (United States); Univ. Paris-Saclay, Orsay (France)] (ORCID:0009000584858729) AU - Tavakoli, Amin [California Institute of Technology (CalTech), Pasadena, CA (United States)] AU - Dharuman, Gautham [Argonne National Laboratory (ANL), Argonne, IL (United States)] AU - Yang, Jason [California Institute of Technology (CalTech), Pasadena, CA (United States)] (ORCID:0000000331841550) AU - Bhethanabotla, Vignesh [California Institute of Technology (CalTech), Pasadena, CA (United States)] (ORCID:0000000194016967) AU - Kaur, Sukhvinder [Elegen Corp, San Carlos, CA (United States)] AU - Hill, Matthew [Elegen Corp, San Carlos, CA (United States)] AU - Ramanathan, Arvind [Argonne National Laboratory (ANL), Argonne, IL (United States)] (ORCID:0000000216225488) AU - Anandkumar, Anima [California Institute of Technology (CalTech), Pasadena, CA (United States)] (ORCID:0000000269746797) AU - Arnold, Frances H. [California Institute of Technology (CalTech), Pasadena, CA (United States)] (ORCID:000000024027364X) PY - 2026 DO - 10.1038/s41467-026-68384-6 UR - https://www.osti.gov/biblio/3014231 ID - 3014231 ER -