TY  - RPRT
TI  - Probing the limits of genetic recoding using multi-omics-guided evolution
AU  - Nyerges, Akos [Harvard Medical School, Boston, MA (United States)] (ORCID:000000021581490X)
AU  - Chiappino-Pepe, Anush [Harvard Medical School, Boston, MA (United States)] (ORCID:000000023993907X)
AU  - Budnik, Bogdan [Harvard Univ., Boston, MA (United States)] (ORCID:0000000336222003)
AU  - Baas-Thomas, Maximilien [Harvard Medical School, Boston, MA (United States)] (ORCID:0000000198219585)
AU  - Rhuby, Elissa [Harvard Medical School, Boston, MA (United States)]
AU  - Flynn, Regan [Harvard Medical School, Boston, MA (United States)]
AU  - Yan, Shirui [Harvard Medical School, Boston, MA (United States); BGI Research, Shenzhen (China)]
AU  - Ostrov, Nili [Harvard Medical School, Boston, MA (United States)]
AU  - Liu, Min [GenScript USA Inc., Piscataway, NJ (United States)]
AU  - Wang, Meizhou [GenScript USA Inc., Piscataway, NJ (United States)]
AU  - Zheng, Qingmei [GenScript USA Inc., Piscataway, NJ (United States)]
AU  - Hu, Fangxiang [GenScript USA Inc., Piscataway, NJ (United States)]
AU  - Chen, Kangming [GenScript USA Inc., Piscataway, NJ (United States)]
AU  - Rudolph, Alexandra [Harvard Medical School, Boston, MA (United States)]
AU  - Chen, Dawn [Harvard Medical School, Boston, MA (United States)] (ORCID:0000000181276014)
AU  - Ahn, Jenny [Harvard Medical School, Boston, MA (United States)] (ORCID:0009000039127162)
AU  - Spencer, Owen [Harvard Medical School, Boston, MA (United States)]
AU  - Ayalavarapu, Venkat [Harvard Medical School, Boston, MA (United States)]
AU  - Tarver, Angela [USDOE Joint Genome Institute (JGI), Berkeley, CA (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)]
AU  - Harmon-Smith, Miranda [USDOE Joint Genome Institute (JGI), Berkeley, CA (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)] (ORCID:0000000239801820)
AU  - Hamilton, Matthew [USDOE Joint Genome Institute (JGI), Berkeley, CA (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)]
AU  - Blaby, Ian [USDOE Joint Genome Institute (JGI), Berkeley, CA (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)] (ORCID:0000000216313154)
AU  - Yoshikuni, Yasuo [USDOE Joint Genome Institute (JGI), Berkeley, CA (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)] (ORCID:000000028372640X)
AU  - Hajian, Behnoush [Broad Institute of MIT and Harvard, Cambridge, MA (United States)]
AU  - Jin, Adeline [GenScript USA Inc., Piscataway, NJ (United States)]
AU  - Kintses, Balint [HUN-REN Biological Research Centre (HUN-REN BRC), Szeged (Hungary)] (ORCID:0000000308440310)
AU  - Szamel, Monika [HUN-REN Biological Research Centre (HUN-REN BRC), Szeged (Hungary)]
AU  - Seregi, Viktoria [HUN-REN Biological Research Centre (HUN-REN BRC), Szeged (Hungary)]
AU  - Shen, Yue [BGI Research, Shenzhen (China); BGI Research, Changzhou (China)] (ORCID:0000000232767295)
AU  - Li, Zilong [GenScript USA Inc., Piscataway, NJ (United States)]
AU  - Church, George M. [Harvard Medical School, Boston, MA (United States); Harvard Univ., Boston, MA (United States)] (ORCID:0000000162329969)
PY  - 2026
DO  - 10.1038/s41467-026-74300-9
UR  - https://www.osti.gov/biblio/3382431
ID  - 3382431
ER  -