TY - RPRT TI - Small-molecule modulation of β-arrestins AU - Kahsai, Alem W. [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000192724484) AU - Pakharukova, Natalia [Duke University, Durham, NC (United States). Medical Center] AU - Kwon, Henry Y. [Duke University, Durham, NC (United States). Medical Center; Henry Ford Hospital, Detroit, MI (United States)] (ORCID:0000000170319023) AU - Shah, Kunal S. [Duke University, Durham, NC (United States). Medical Center; Cedars‐Sinai Medical Center, Los Angeles, CA (United States)] (ORCID:0000000199063025) AU - del Real, Caroline T. [Duke University, Durham, NC (United States). Medical Center] (ORCID:0009000274664435) AU - Shreiber, Bowie N. [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000331344431) AU - Liang-Lin, Jason G. [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000342776694) AU - Shim, Paul J. [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000266108378) AU - Lee, Mason A. [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000187723567) AU - Ngo, Van A. [Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States). National Center for Computational Sciences (NCCS)] (ORCID:0000000183501203) AU - Schwalb, Allison M. [Duke University, Durham, NC (United States). Medical Center] AU - Pham, Uyen [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000220386794) AU - Chundi, Anand [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000181487479) AU - Jiang, Haoran [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000159163072) AU - Flores-Espinoza, Emmanuel [New York University (NYU), NY (United States). College of Dentistry] (ORCID:0000000278897458) AU - Liu, Samuel [Duke University, Durham, NC (United States). Medical Center] AU - Nibley, Preston C. [Duke University, Durham, NC (United States). Medical Center] AU - Bassford, Dana K. [Duke University, Durham, NC (United States). Medical Center] AU - Hahn, Hyunggu [New York University (NYU), NY (United States). College of Dentistry] (ORCID:0000000335327671) AU - Kunzle, Cal A. [Duke University, Durham, NC (United States). Medical Center] AU - Thomas, Brittany N. [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000183177538) AU - Kim, Jihee [Duke University, Durham, NC (United States). Medical Center] AU - Zhou, Yang [Duke University, Durham, NC (United States). Medical Center] AU - Wang, Jialu [Duke University, Durham, NC (United States). Medical Center] AU - Zhang, Xingdong [Duke University, Durham, NC (United States). Medical Center] AU - Smith, Jeffrey S. [Duke University, Durham, NC (United States). Medical Center; Massachusetts General Hospital, Boston, MA (United States); Harvard Medical School, Boston, MA (United States)] AU - Rein, Lindsay A. M. [Duke University, Durham, NC (United States). Medical Center] AU - Thomsen, Alex R. B. [New York University (NYU), NY (United States). College of Dentistry] (ORCID:0000000316388911) AU - Shenoy, Sudha K. [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000225654663) AU - Rajagopal, Sudarshan [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000234435040) AU - Shi, Lei [National Institutes of Health (NIH), Baltimore, MD (United States)] (ORCID:000000024137096X) AU - Ahn, Seungkirl [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000156813789) AU - Rockman, Howard A. [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000329211584) AU - Masoudi, Ali [Duke University, Durham, NC (United States). Medical Center] AU - Lefkowitz, Robert J. [Duke University, Durham, NC (United States). Medical Center] (ORCID:0000000314727545) PY - 2026 DO - 10.1038/s41586-026-10683-5 UR - https://www.osti.gov/biblio/3385011 ID - 3385011 ER -