NASA NTRS · 19920002410
Intranasal scopolamine preparation and method
Abstract
A new method and preparation for intranasal delivery of scopolamine provides a safe and effective treatment for motion sickness and other conditions requiring anticholinergic therapy. The preparation can be in the form of aqueous nasal drops, mist spray, gel or oinment. Intranasal delivery of scopolamine has similar bioavailability and effect of intravenous delivery and is far superior to oral dosage. Scopolamine is prepared in a buffered saline solution at the desired dosage rate for effective anticholinergic response.
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Putcha, Lakshmi, Cintron, Nitza M.. 1991-09-25. Intranasal scopolamine preparation and method. https://ntrs.nasa.gov/citations/19920002410
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