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NASA NTRS · 19930000116

Bioconvective Assay As Alternative To Draize Test

Abstract

Protocol to determine toxicities of chemicals implemented relatively cheaply by use of equipment and materials packaged in convenient kit form. Tests involve observation of macroscopic patterns formed at high concentrations of free-swimming protozoan species Tetrahymena pyriformis in liquid media. Provides more-sensitive indication of toxicity and costs less. Given that there are no data on toxicities of 70 to 80 percent of commercial chemicals, high cost of, and current opposition to, testing on higher animals, new protocol helps meet pressing need.

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BibTeXRIS

Noever, David A., Matsos, Helen C.. 1993-02-01. Bioconvective Assay As Alternative To Draize Test. https://ntrs.nasa.gov/citations/19930000116

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