NASA NTRS · 19930000307
Monatomic Oxygen Makes Materials Biocompatible
Abstract
Treatment with monatomic oxygen activates surfaces of biomedical and biotechnical materials without adversely affecting properties of bulk and without introducing toxic or otherwise dangerous solvent residues. Treatment used to create carpetlike texture increasing surface area and encouraging cells to adhere and grow. On silicone tubing for vascular implants, carpet surface improves acceptance by body. On polymer beads and vessels, surface increases effectiveness of growing, storing, and separating cell cultures. Monatomic oxygen relatively abundant in upper atmosphere of Earth, thus treatments carried out on Space Shuttle missions. Alternatively, one of several high-energy neutral-beam devices used in terrestrial laboratories.
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Spaulding, Glenn, Koontz, Steven L.. 1993-05-01. Monatomic Oxygen Makes Materials Biocompatible. https://ntrs.nasa.gov/citations/19930000307
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