NASA NTRS · 19940030726
Multi-cellular, three-dimensional living mammalian tissue
Abstract
The present invention relates to a multicellular, three-dimensional, living mammalian tissue. The tissue is produced by a co-culture process wherein two distinct types of mammalian cells are co-cultured in a rotating bioreactor which is completely filled with culture media and cell attachment substrates. As the size of the tissue assemblies formed on the attachment substrates changes, the rotation of the bioreactor is adjusted accordingly.
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Goodwin, Thomas J., Wolf, David A.. 1994-05-03. Multi-cellular, three-dimensional living mammalian tissue. https://ntrs.nasa.gov/citations/19940030726
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