A semi-automatic method for left ventricle volume estimate: an in vivo validation study

Corsi, C.; Lamberti, C.; Sarti, A.; Saracino, G.; Shiota, T.; Thomas, J. D.

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NASA NTRS · 20040087439

A semi-automatic method for left ventricle volume estimate: an in vivo validation study

Corsi, C.·Lamberti, C.·Sarti, A.·Saracino, G.·Shiota, T.·Thomas, J. D.

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Abstract

This study aims to the validation of the left ventricular (LV) volume estimates obtained by processing volumetric data utilizing a segmentation model based on level set technique. The validation has been performed by comparing real-time volumetric echo data (RT3DE) and magnetic resonance (MRI) data. A validation protocol has been defined. The validation protocol was applied to twenty-four estimates (range 61-467 ml) obtained from normal and pathologic subjects, which underwent both RT3DE and MRI. A statistical analysis was performed on each estimate and on clinical parameters as stroke volume (SV) and ejection fraction (EF). Assuming MRI estimates (x) as a reference, an excellent correlation was found with volume measured by utilizing the segmentation procedure (y) (y=0.89x + 13.78, r=0.98). The mean error on SV was 8 ml and the mean error on EF was 2%. This study demonstrated that the segmentation technique is reliably applicable on human hearts in clinical practice.

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NASA Discipline Cardiopulmonary Validation Studies Non-NASA Center NASA Program Biomedical Research and Countermeasures Magnetic Resonance Imaging/methods/statistics & numerical data Ventricular Dysfunction, Left/diagnosis/physiopathology/ultrasonography Ventricular Function, Left/physiology Heart Ventricles/ultrasonography Echocardiography, Three-Dimensional/methods/statistics & numerical data Reproducibility of Results Linear Models Image Processing, Computer-Assisted Stroke Volume/physiology Comparative Study Human Regression Analysis

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Corsi, C., Lamberti, C., Sarti, A., Saracino, G., Shiota, T., Thomas, J. D.. 2001-01-01. A semi-automatic method for left ventricle volume estimate: an in vivo validation study. https://ntrs.nasa.gov/citations/20040087439

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