Ribosomal RNA: a key to phylogeny

Olsen, G. J.; Woese, C. R.

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NASA NTRS · 20050000535

Ribosomal RNA: a key to phylogeny

Olsen, G. J.·Woese, C. R.

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Abstract

As molecular phylogeny increasingly shapes our understanding of organismal relationships, no molecule has been applied to more questions than have ribosomal RNAs. We review this role of the rRNAs and some of the insights that have been gained from them. We also offer some of the practical considerations in extracting the phylogenetic information from the sequences. Finally, we stress the importance of comparing results from multiple molecules, both as a method for testing the overall reliability of the organismal phylogeny and as a method for more broadly exploring the history of the genome.

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NASA Program Exobiology NASA Discipline Number 52-30 NASA Discipline Exobiology Non-NASA Center Review, Academic Review RNA, Ribosomal/classification/genetics DNA, Ribosomal/classification/genetics Phylogeny Support, U.S. Gov't, Non-P.H.S Sequence Alignment/methods Comparative Study

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Olsen, G. J., Woese, C. R.. 1993-01-01. Ribosomal RNA: a key to phylogeny. https://ntrs.nasa.gov/citations/20050000535

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