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DOE OSTI · 1078543

Micro-Anatomy Imager

Demos, Stavros G.
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Abstract

The Micro-Anatomy Imager provides noncontact visualization of tissue cell structure and organization to detect abnormal changes associated with the presence of disease such as cancer. For the first time, visualization of the structure and function of live cells at the tissue level is possible (Figures 1 and 2). Images can be acquired without any need for prior preparation of the tissue or use of contrast agents. The technology can be used to rapidly evaluate excised tissue specimens of patients during surgery to determine if, for example, all cancer has been removed. The instrument addresses current limitations in histological examination of tissue specimens obtained during surgery to help advance patient care and reduce healthcare costs. The technology is simple and inexpensive. This technology can also be used in experimental in vivo animal research, to enhance education in biology and, in future implementation, as an imaging modality that can visualize cancer lesions in real time to guide surgery.

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Demos, Stavros G.. 2013-04-26. Micro-Anatomy Imager. https://doi.org/10.2172/1078543

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