DOE OSTI · 1088677
Data transformation methods for multiplexed assays
Abstract
Methods to improve the performance of an array assay are described. A correlation between fluorescence intensity-related parameters and negative control values of the assay is determined. The parameters are then adjusted as a function of the correlation. As a result, sensitivity of the assay is improved without changes in its specificity.
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Tammero, Lance F. Bentley, Dzenitis, John M, Hindson, Benjamin J. 2013-07-23. Data transformation methods for multiplexed assays. https://www.osti.gov/biblio/1088677
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