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DOE OSTI · 1150711

Fluidics platform and method for sample preparation and analysis

Benner, W. Henry·Dzenitis, John M.·Bennet, William J.·Baker, Brian R.
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Abstract

Herein provided are fluidics platform and method for sample preparation and analysis. The fluidics platform is capable of analyzing DNA from blood samples using amplification assays such as polymerase-chain-reaction assays and loop-mediated-isothermal-amplification assays. The fluidics platform can also be used for other types of assays and analyzes. In some embodiments, a sample in a sealed tube can be inserted directly. The following isolation, detection, and analyzes can be performed without a user's intervention. The disclosed platform may also comprises a sample preparation system with a magnetic actuator, a heater, and an air-drying mechanism, and fluid manipulation processes for extraction, washing, elution, assay assembly, assay detection, and cleaning after reactions and between samples.

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BibTeXRIS

Benner, W. Henry, Dzenitis, John M., Bennet, William J., Baker, Brian R.. 2014-08-19. Fluidics platform and method for sample preparation and analysis. https://www.osti.gov/biblio/1150711

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