DOE OSTI · 1207279
Genetic barcodes
Abstract
Herein are described multicolor FISH probe sets termed "genetic barcodes" targeting several cancer or disease-related loci to assess gene rearrangements and copy number changes in tumor cells. Two, three or more different fluorophores are used to detect the genetic barcode sections thus permitting unique labeling and multilocus analysis in individual cell nuclei. Gene specific barcodes can be generated and combined to provide both numerical and structural genetic information for these and other pertinent disease associated genes.
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Weier, Heinz -Ulrich G. 2015-08-04. Genetic barcodes. https://www.osti.gov/biblio/1207279
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