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DOE OSTI · 1602738

Liquid Chromatography Mass Spectrometry Instrumentation and Methodology

Wong, Camille Hing
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Abstract

This report reviews instrumentation and techniques utilized in liquid chromatography mass spectrometry (LC-MS). The analytical advantages and disadvantages of each major component of different LC-MS systems are discussed, along with a comparison between LC-MS, liquid chromatography tandem mass spectrometry (LC-MS/MS), and gas chromatography mass spectrometry (GC-MS). This report also details future work regarding the use of LC-MS/MS to analyze and identify degradation products from an extensive accelerated aging process of nitroplasticizer (NP). This report is the first of a series on the use of LC-MS to understand the degradation mechanisms of NP.

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Wong, Camille Hing. 2020-03-03. Liquid Chromatography Mass Spectrometry Instrumentation and Methodology. https://doi.org/10.2172/1602738

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