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DOE OSTI · 1633031

Solving a furan fatty acid biosynthesis puzzle

Yu, Xiao-Hong·Shanklin, John
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Abstract

Furan fatty acids (FuFAs), characterized by a central furan moiety, are widely dispersed in nature, but their biosynthetic origins are not clear. A new study from Lemke et al. employs a full court press of genetics, genomics, biochemical, and advanced analytical techniques to dissect the biosynthetic pathway of mono- and dimethyl FuFAs and their intermediates in two related bacteria. Overall these findings lay the foundation both for detailed study of these novel enzymes and for gaining further insights into FuFA functions.

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Yu, Xiao-Hong, Shanklin, John. 2020-07-17. Solving a furan fatty acid biosynthesis puzzle. https://doi.org/10.1074/jbc.h120.014701

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