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DOE OSTI · 1637795

Host cells and methods for oxidizing aromatic amino acids

Lee, Taek Soon·Satoh, Yasuharu·Keasling, Jay D.
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Abstract

The present invention provides for a method of producing an oxidation product of an aromatic amino acid in a genetically modified host cell. The method comprises culturing the genetically modified host cell under a suitable condition such that the culturing results in the genetically modified host cell producing oxidation product of an aromatic amino acid. The host cell comprises an enzyme capable of catalyzing the oxidation of aromatic amino acid. In some embodiments, the host cell is capable of biosynthesizing BH4 or MH4 from GTP.

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37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY59 BASIC BIOLOGICAL SCIENCES

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Lee, Taek Soon, Satoh, Yasuharu, Keasling, Jay D.. 2020-03-24. Host cells and methods for oxidizing aromatic amino acids. https://www.osti.gov/biblio/1637795

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