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DOE OSTI · 1650872

Selective high-affinity polydentate ligands and methods of making such

DeNardo, Sally J.·Denardo, Gerald L.·Balhorn, Rodney L.
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Abstract

This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.

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BibTeXRIS

DeNardo, Sally J., Denardo, Gerald L., Balhorn, Rodney L.. 2020-05-12. Selective high-affinity polydentate ligands and methods of making such. https://www.osti.gov/biblio/1650872

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