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DOE OSTI · 1661913

Omics-Lethal Human Viruses, Influenza A Experiment ICL103

Anderson, Lindsey N.·Eisfeld, Amie J.·Waters, Katrina M.
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Abstract

The purpose of this experiment was to evaluate the human host response to Influenza A wild-type (H5N1) virus and mutant viruses. Sample data was obtained for human lung adenocarcinoma cell line (Calu-3) infected with WT Influenza A/Vietnam/1203/2004 (H5N1, VN1203) and mutant viruses PB2-K627E and NS1-trunc124 for mRNA, miRNA, proteomics, lipidomics, and metabolomics data analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Leveraging unique high-resolution Omics capabilities for proteomics, metabolomics, lipidomics, and transcriptomics dataset download each have a direct relationship to a primary sample submission corresponding to a specific Influenza A virus infection.

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59 BASIC BIOLOGICAL SCIENCESBioProject Accession Number [NCIT:C175890]Data Download [schema:DataDownload]data transformation [SIO:000594]differential expression analysis [SWO:7000018]Gene expression profile data [edam.data:0928]Human virus [NCIT:C14317]Immune Response [GO:0006955]Influenza A virus [NCBITAXON:11320]Mass spectrometry data [edam.data:2536]MassIVE dataset identifier [MS:1002487]Multi-omics [edam.topic:4021]Omics [edam.topic:3391]Time Sampled Measurement Datasets [IAO:0000584]Virology [edam.topic:0781]

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Anderson, Lindsey N., Eisfeld, Amie J., Waters, Katrina M.. 2021-01-18. Omics-Lethal Human Viruses, Influenza A Experiment ICL103. https://doi.org/10.25584/lhvicl103%2F1661913

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