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DOE OSTI · 1661922

Omics-Lethal Human Viruses, Interferon-Stimulated Response Experiment IFNaHUH001

Anderson, Lindsey N.·Eisfeld, Amie J.·Waters, Katrina M.
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Abstract

The purpose of this experiment was to evaluate the human host cellular response to treatment with and without interferon alpha/beta (IFNα/β) treatment. Sample time course data was obtained from human hepatoma carcinoma cells (HUH-7) expressing transcriptional activation protein VP30, stably transfected with the Ebola VP30 gene for enabling replication of VP30-deficient Ebola virus for transcriptome expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset download have a direct relationship to a primary sample submission corresponding to a specific interferon response to viral infection.

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59 BASIC BIOLOGICAL SCIENCESBioProject Accession Number [NCIT:C175890]Data Download [schema:DataDownload]data transformation [SIO:000594]differential expression analysis [SWO:7000018]Ebola virus [NCBITAXON:186536]Gene expression profile data [edam.data:0928]Human Interferon [NCIT:C20493]Human virus [NCIT:C14317]Immune Response [GO:0006955]Interferon Alpha [NCIT:C20494]Interferon Beta [NCIT:C20495]Omics [edam.topic:3391]Time Sampled Measurement Datasets [IAO:0000584]Virology [edam.topic:0781]

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Anderson, Lindsey N., Eisfeld, Amie J., Waters, Katrina M.. 2021-01-18. Omics-Lethal Human Viruses, Interferon-Stimulated Response Experiment IFNaHUH001. https://doi.org/10.25584/lhvifnaahuhh0011%2F1661922

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