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DOE OSTI · 1661933

Omics-Lethal Human Viruses, MERS-CoV Experiment MCL002

Anderson, Lindsey N.·Eisfeld, Amie J.·Waters, Katrina M.
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Abstract

The purpose of this experiment was to evaluate the human host response to wild-type Middle Eastern Respiratory Syndrome coronavirus (icMERS) and icMERS-CoV mutants icMERS-RFP, icMERS-DNSP16, and icMERS-d4B virus infection. Sample data was obtained from human bronchial epithelial cells (Calu-3 clone 2B4) for proteome, metabolome, and lipidome expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Leveraging unique high-resolution Omics capabilities for proteomics, metabolomics, and lipidomics dataset download each have a direct relationship to a primary sample submission corresponding to a specific MERS-CoV virus infection.

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59 BASIC BIOLOGICAL SCIENCESData Download [schema:DataDownload]data transformation [SIO:000594]differential expression analysis [SWO:7000018]Human virus [NCIT:C14317]Immune Response [GO:0006955]Mass spectrometry data [edam.data:2536]MassIVE dataset identifier [MS:1002487]Middle East respiratory syndrome-related coronavirus [NCBITAXON:1335626]Multi-omics [edam.topic:4021]Omics [edam.topic:3391]Time Sampled Measurement Datasets [IAO:0000584]Virology [edam.topic:0781]

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Anderson, Lindsey N., Eisfeld, Amie J., Waters, Katrina M.. 2021-01-18. Omics-Lethal Human Viruses, MERS-CoV Experiment MCL002. https://doi.org/10.25584/lhvmcl002%2F1661933

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