DOE OSTI · 1771770
Advanced drug development and manufacturing
Abstract
X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical. For estimating the binding selectivities of a chemical versus chemical analogs, for measuring post translational modification of proteins, and for drug manufacturing.
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Birnbaum, Eva R., Koppisch, Andrew T., Baldwin, Sharon M., Warner, Benjamin P., McCleskey, T. Mark, Berger, Jennifer A., Stewart, Jeffrey J., Harris, Michael N., Burrell, Anthony K.. 2020-12-29. Advanced drug development and manufacturing. https://www.osti.gov/biblio/1771770
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