DOE OSTI · 1840386
Compositions and methods for modulating kinase activity
Abstract
The present invention features an antibody mimetic, or an antigen binding fragment thereof, that specifically binds to an allosteric site of Aurora A kinase, therapeutic compositions comprising this antibody mimetic, and the use of the monobody to modulate Aurora A kinase for the treatment of cancer.
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Kern, Dorothee, Zorba, Adelajda. 2021-08-31. Compositions and methods for modulating kinase activity. https://www.osti.gov/biblio/1840386
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