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DOE OSTI · 2293577

Accelerating Engineered Microbe Optimization through Machine Learning and Multi-Omics Datasets [Abstract]

Kim, Joonhoon
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Abstract

The Agile Biofoundry (ABF) is a multi-national lab consortium funded by the DOE Bioenergy Technologies Office that has developed a biofoundry enabling the rapid deployment of bioproducts into the market. The ABF is a flexible platform that can adjust to the needs of numerous government, academic and industrial partners, thus enabling them to rapidly develop and optimize the production of a wide range of bioproducts. To demonstrate this capability, three ABF labs (NTESS, LBNL, and PNNL) have collaborated with the biomanufacturer Lygos, Inc. to use the ABF to demonstrate a high-throughput Design-Build-Test-Learn (DBTL) engineering cycle incorporating multi-omics analysis and machine learning with best in industry cycle times.

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Kim, Joonhoon. 2024-02-01. Accelerating Engineered Microbe Optimization through Machine Learning and Multi-Omics Datasets [Abstract]. https://doi.org/10.2172/2293577

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