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DOE OSTI · 23200813

Microsecond Pulsed Electric Fields: An Effective Way to Selectively Target and Radiosensitize Medulloblastoma Cancer Stem Cells

Tanori, Mirella·Casciati, Arianna·Zambotti, Alessandro·Pinto, Rosanna·Gianlorenzi, Isabella·others, and
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Abstract

Cancer stem cells constitute an endless reserve for the maintenance and progression of tumors, and they could be the reason for conventional therapy failure. New therapeutic strategies are necessary to specifically target them. In this context, microsecond pulsed electric fields have been selected to expose D283Med cells, a human medulloblastoma cell line resulted to be rich in cancer stem cells, and normal human astrocytes.

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62 RADIOLOGY AND NUCLEAR MEDICINEELECTRIC FIELDSFAILURESNEOPLASMSPULSESSTEM CELLSTHERAPY

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BibTeXRIS

Tanori, Mirella, Casciati, Arianna, Zambotti, Alessandro, Pinto, Rosanna, Gianlorenzi, Isabella, others, and. 2021-04-15. Microsecond Pulsed Electric Fields: An Effective Way to Selectively Target and Radiosensitize Medulloblastoma Cancer Stem Cells. https://doi.org/10.1016/j.ijrobp.2020.11.047

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