DOE OSTI · 3366501
Multi-omics data resource: Data package 24 (Pck024)
Abstract
The data package consists of isolated pancreatic islets from 3 human donors treated with IL-1β, IFNγ or IL-1β + IFNγ for 6 h and IL-1β, IFNγ, IL-1β + IFNγ, IL-1β + IFNγ + NMMA or NMMA for 18 h and submitted for scRNA-seq. This study examines cytokine-stimulated changes in gene expression in human islets using single-cell RNA sequencing. Data contributors: Jennifer S Stancill & John A Corbett: Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, USA Data repository: GSE251730 Publication: 10.1093/function/zqae015
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Sarkar, Soumyadeep [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], Flores, Javier E [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], Nune, Navaj [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], Ramos-Rodriguez, Mireia, Kulkarni, Abhishek, Ives, Ashley N [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], Hammoud, Batoul, Wu, Wenting, Yi, Xiaoyan, Roca-Rivada, Arturo, Maestas, Marlie M, Gluth, Austin, Elliott, Emily C [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], You, Youngki [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], Krishnan, Preethi, Syed, Farooq, Kim, Young-Mo [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] (ORCID:0000000289727593), Kyle, Jennifer E [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], Kono, Tatsuyoshi, Fulcher, James M [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], Sims, Emily K, Tersey, Sarah A, Sussel, Lori, Webb-Robertson, Bobbie-Jo Mary [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], Qian, Weijun [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] (ORCID:0000000253932827), Zhang, Tong [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], Metz, Thomas O [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] (ORCID:0000000160493968), Millman, Jeffrey R, Evans-Molina, Carmella, Pasquali, Lorenzo, Mirmira, Raghavendra G, Eizirik, Decio L, Nakayasu, Ernesto S [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] (ORCID:0000000240562695). 2026-05-25. Multi-omics data resource: Data package 24 (Pck024). https://doi.org/10.25584/3366501
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