DOE OSTI · 3375089
Human Lung Cellular Response to HCoV-229E Infection, Post-Translational Modification Proteomics Time Course (ACS-TZ-DP6)
Abstract
The purpose of this experiment was to evaluate the human lung cellular response to wild type human coronavirus strain 229E (HCoV-229E) infection. Sample data was obtained for mock-infected and HCoV-229E infected immortalized human lung epithelial cells (A549) (MOI 3) and immortalized human lung fibroblasts (MRC-5) (MOI 3). Whole cell lysates were collected at 8, 16, and 24 hours post infection and were processed for post translational modification (PTM) proteomics analysis to determine the HCoV-229E phosphoproteome, redox proteome, and acetylation proteome.
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Sims, Amy C [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], Zhang, Tong [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)], Waters, Katrina M [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)] (ORCID:0000000346965396). 2026-06-01. Human Lung Cellular Response to HCoV-229E Infection, Post-Translational Modification Proteomics Time Course (ACS-TZ-DP6). https://doi.org/10.25584/3375089
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