Base editing HbS to HbG-Makassar improves hemoglobin function supporting its use in sickle cell disease

Keep this discovery

Explore connections, maps & timelines

Kostamo, Zachary, Ortega, Manuel (ORCID:0000000322139516), Xu, Chavonna, Feliciano, Patricia, Budak, Elizabeth (ORCID:000900031558511X), Lam, Daisy, Winton, Valerie, Jenkins, Rebecca, Venugopal, Archita, Zhang, Margaret, Jamieson, John, Coisman, Brent, Goldsborough, Kennedy, Hernandez, Britney, Kanne, Celeste (ORCID:000900020547905X), Evans, Erica, Zgodny, Jordan, Zhang, Yankai, Darazim, Jawa, Patel, Ashwin (ORCID:0000000300753304), Pendergast, Michael (ORCID:0009000035600290), Manis, John (ORCID:000000023630778X), Hartigan, Adam, Ciaramella, Giuseppe (ORCID:0000000333397211), Lee, Seung-Joo, Chu, S. (ORCID:0000000283335409), Sheehan, Vivien (ORCID:0000000328372255). 2025-02-07. Base editing HbS to HbG-Makassar improves hemoglobin function supporting its use in sickle cell disease. https://doi.org/10.1038/s41467-025-56578-3

Cite the original work for its findings. Save a collection to share your selection of sources.